Activated Protein CV deficient
APCRV (Activated Protein C Resistance V)
For diagnostic samples, all probes in the initial panel will be performed. The initial panel includes testing for the following abnormalities using the probes listed:
t(8;21), [M2], RUNX1T1/RUNX1
t(15;17), [M3], PML/RARA
11q23 rearrangement, [M0-M7], MLL (KMT2A)
inv(16), [M4, Eos], MYH11/CBFB
Based on the results from the initial panel, reflex testing may be performed to identify the following abnormalities:
t(6;9), [M2,M4], DEK/NUP214
inv(3) or t(3;3), [M1,2,4,6,7], RPN1/MECOM
t(8;16), [M4,M5], MYST3/CREBBP
t(1;22), [M7], RBM15/MKL1*
*The RBM15/MKL1 probe set will only be used to test patients with a suspected or confirmed diagnosis of M7 or to confirm a t(1;22) identified by chromosome analysis.
-When a MLL (KMT2A) rearrangement is identified, reflex testing will be performed to identify the translocation partner. Probes include identification of t(4;11)(q21;q23) AFF1/MLL, t(6;11)(q27;q23) MLLT4/MLL, t(9;11)(p22;q23) MLLT3/MLL, t(10;11)(p13;q23) MLLT10/MLL, t(11;16)(q23;p13.3) MLL/CREBBP, t(11;19)(q23;p13.1) MLL/ELL, or t(11;19)(q23;p13.3) MLL/MLLT1.
-When 3 copies of MECOM are observed with no fusion with RPN1, reflex testing using the MECOM/RUNX1 probe set will be performed to identify a potential t(3;21)(q26.2;q22) rearrangement.
-When 3 copies of RPN1 are observed with no fusion with MECOM, reflex testing using the PRDM16/RPN1 probe set will be performed to identify a potential t(1;3)(p36;q21).
-When 3 copies of RARA are observed with no fusion with PML, reflex testing using the 5'RARA/3'RARA rearrangement probe set will be performed to identify a potential variant translocation involving RARA; example: t(17;var)( q21;?).
-In the absence of BCR/ABL1 fusion, when an extra signal for ABL1 is identified, reflex testing will be performed using the ABL1 break-apart probe set to evaluate for the presence or absence of an ABL1 rearrangement.
If the patient is being treated for known abnormalities, indicate which probes should be used.
If this test is ordered and the laboratory is informed that the patient is on a Children's Oncology Group (COG) protocol, this test will be canceled and automatically reordered by the laboratory as COGMF / Acute Myeloid Leukemia (AML), Children's Oncology Group Enrollment Testing, FISH, Varies.
2-Methylbutyryl Glycinuria 2-Methylbutyryl-CoA Dehydrogenase Deficiency EE (Ethylmalonic Encephalopathy) Ethylmalonic Encephalopathy (EE) GA 1 (Glutaric Acidemia Type 1) GA 2 (Glutaric Acidemia Type 2) GA II (Glutaric Acidemia Type II) GAII (Glutaric Acidemia Type 2) GCDH (Glutaryl-CoA Dehydrogenase) Deficiency Glutaric Acidemia (GA) Glutaric Acidemia Type 2 Glutaric Acidemia Type I (GA I) Glutaric Acidemia Type II (GA II) Glutaryl-CoA Dehydrogenase (GCDH) Deficiency Isovaleric Acidemia (IVA) Isovaleryl-CoA Dehydrogenase (IVD) IVA (Isovaleric Acidemia) MADD MCAD (Medium-Chain Acyl-CoA Dehydrogenase) Deficiency MCKAT (Medium-Chain 3-Ketoacyl-CoA Thiolase) Deficiency Medium-Chain 3-Ketoacyl-CoA Thiolase (MCKAT) Deficiency Medium-Chain Acyl-CoA Dehydrogenase (MCAD) Deficiency SBCAD (Short/Branched-Chain Acyl-CoA Dehydrogenase) Deficiency SCAD (Short-Chain Acyl-CoA Dehydrogenase) Deficiency Short-Chain Acyl-CoA Dehydrogenase (SCAD) Deficiency Short/Branched-Chain Acyl-CoA Dehydrogenase (SBCAD) Deficiency n-Acetylglycine n-Propionylglycine Isobutyrylglycine Ethylmalonic acid n-Butyrylglycine 2-Methylsuccinic acid 2-Methylbutyrylglycine Isovalerylglycine Glutaric acid 3-Methylcrotonylglycine n-Tiglylglycine 3-Methylglutaconic acid n-Hexanoylglycine n-Octanoylglycine 3-Phenylpropionylglycine trans-Cinnamoylglycine Suberylglycine Dodecanedioic acid Tetradecanedioic acid Hexadecanedioic acid
If the result is 8.0 mcg/mL or less, then adalimumab antibody test will be performed at an additional charge.
Alkaline Phosphatase Isoenzymes
Ascaris lumbricoides, Common Roundworm
Brassica oleracea var. italica Calabrese Purple Cauliflower Romanesco Spear Cauliflower Winter Cauliflower
Galactose IgE Galactose-alpha-1,3 Alpha-Gal
Galactose-alpha-1,3-galactose, IgE; Beef, IgE; Pork, IgE; Lamb, IgE; Milk, IgE
IgE Antibodies, Multi-Allergen
Includes: Alternaria tenuis, Aspergillus fumingatus, Candida albicans, Cladosporium herbarum, Helminthosporium halodes, Penicillium notatum
Medicago sativa grass FORWARD
Aspergillus oryzae; Occupational, Alpha-amylase
Lactoalbumin, Alpha; Milk component
Hachiku Madaka Moso Phyllostachys pubescens Pubescent Bamboo
Beech WheatCanadian BuckwheatFagopyrumFagopyrum esculentumFrench Wheat
Budgie DroppingsMelopsittacus undulatus droppingsParakeet droppings
Brassica oleracea var. botrytis Broccoflower Calabrese Romanesco
Castanea sativaChestnutEuropean ChestnutSweet Chestnut
Chestnut sweet, nut Chestnut, sweet, Nuts European Chestnut Nuts, Chestnut, sweet Spanish Chestnut
Ceylon cinnamon Cinnamomum spp. True cinnamon
CilantroCoriander, herbCoriandrum sativumHerb, Coriander
Brambling FeathersBunting FeathersCardinal FeathersCrossbill FeathersFeathers, finchGoldfinch FeathersGrosbeak FeathersJunco FeathersLinnet FeathersLonchura domestricaSiskin FeathersSparrow FeathersTowhee Feathers
Apple Banana IgE Antibodies, Multi-Allergen Peach Pear
Includes testing for apple, banana, peach, and pear allergen.
Barley IgE Antibodies, Multi-Allergen Rice Rye Wheat
Includes testing for barley, rice, rye, and wheat allergen.
Ginger Root Green (Fresh) Ginger Zingiber officinale
Cyamopsis psoraloidesCyamopsis tetragonolobaCyamopsis tetragonolobus
Cricetidae Cricetus Cricetus - common hamster epithelium Mesocricetus auratus - Siberian hamster epithelium, dwarf hamster epithelium Phodopus sungorus - golden hamster epithelium
Hypersensitivity Pneumonitis (HP)
Alternaria tenuis/alternata IgG, Aspergillus fumigatus IgG, Aureobasidium pullulans IgG, Micropolyspora faeni IgG, Penicillium Chrysogenum/notatum IgG, Phoma betae IgG, Thermoactinomyces vulgaris IgG, Trichodema viride IgG
Mutton (Ovis Spp.)
Cicer lensLens culinarisLens esculentaLentilla lens
Cantaloupe Common Melon Cucumis Melos spp. Honeydew
Aedes communis Insect, Mosquito spp.
Mouse Epithelium, IgE
Morus alba Mulberry Red Mulberry, tree Silkworm Mulberry Tree, Mulberry White Mulberry
Greek Oregano Oreganum Origanum vulgare Wild marjoram
Carciica papaya Papaw Papaya fruit Paw Paw Tree Melon
Red Bell Pepper
Green Bell Pepper
Ground Nut Monkey Nut Glycinin (h 1 and h 3) Conglutin (h 2) A bet v 1-homologous allergen (h 8) Group 1 Fagales-related protein (h 8) PR-10 Protein (h 8) Non-specific Lipid Transfer Protein (ns-LTP) (h 9) PR-14 Protein (h 9)
Bet v2 Profilin
Testing begins with analysis of peanut IgE. If peanut IgE is negative (<0.10 kU/L), testing is completed.
If peanut IgE is detectable (> or =0.10 kU/L), then the 7 peanut components (Ara h 2, Ara h 1, Ara h 3, Ara h 6, Ara h 8, and Ara h 9 and profilin Betv2) are performed at an additional charge.
The determination of the relative amount of IgE antibody to total peanut, and IgE antibodies to specific peanut components, can aid in assessment of the potential strength and type of allergenic response to peanuts.
IgE antibody to total peanut extract will be tested.
If detectable total peanut IgE antibody is present, additional specific peanut allergen antibody testing will be performed. This is comprised of testing for IgE antibodies to the potential allergens Ara h 2, Ara h 1, Ara h 3, Ara h 6, Ara h 8, Ara h 9, and profilin Bet v2.
BenzylpenicilloylPCN (use this alias for C7000988 SmithKline ONLY)Penicilloyl GIntravenous Penicillin
Penicilloyl V Phenoxymethylpenicilloyl Oral Penicillin
Boar epithelium Hog epithelium Pig epithelium Sus scrofa Swine epithelium Hog
City Pigeon Feathers Feathers, Pigeon Feral Pigeon Feathers Town Pigeon Feathers
Blue Bread Seed Poppy Opium Poppy Papaver somniferum White Poppy
Cucumis pepo Cucurbita pepo Curubita mixta Curubita moschata Cururbita maxima Seed, pumpkin
P. vulgaris var. humilisP. vulgaris var. mexicanusPhaseolus vulgaris
English plantain, Lamb's Quarters, Mugwort, Scale, and Western Ragweed allergen
English Plantain, Lamb's Quarters, Russian Thistle, Sorrel
Giant Ragweed, Short Ragweed, Western Ragweed
Alpha 2 Plasmin Inhibitor Antiplasmin Antiplasmin, Functional, Plasma Functional Antiplasmin Plasmin Inhibitor
AFP (Alpha-Fetoprotein); AFP-AF (Alpha-Fetoprotein, Amniotic Fluid); Alpha Fetoprotein, Amniotic Fluid; Alpha-Fetoprotein, Amniotic Fluid; Fetoprotein, Amniotic Fluid
Alpha Glycoprotein Subunit Alpha Subunit, HCG Alpha-HCG (Human Chorionic Gonadotropin) Alpha-PGH (Pituitary Glycoprotein Hormone) Alpha-Subunit of Pituitary Glycoprotein Hormones (Alpha-PGH), Serum Chorionic Gonadotropins, Alpha-Subunit Glycoprotein Subunit HCG, Alpha Subunit Hormone, Alpha-Subunit PGH (Pituitary Glycoprotein Hormone) Pituitary Glycoprotein Alpha Subunit Pituitary Gonadotropins, Alpha-Subunit
NKH (Nonketotic Hyperglycinemia) Nonketotic Hyperglycinemia (NKH) Serine Biosynthesis Defects Glycine encephalopathy
Cordarone, Desethylamiodarone, Pacerone
This test includes a charge for application of the first probe set (2 FISH probes) and professional interpretation of results.
Additional charges will be incurred for all reflex probes performed. Analysis charges will be incurred based on the number of cells analyzed per probe set. If no cells are available for analysis, no analysis charges will be incurred.
This test does not detect aneuploidy of chromosomes other than 13, 18, 21, X, or Y. This test does not detect other chromosomal or structural anomalies.
Low levels of mosaicism involving chromosomes 13, 18, 21, X, or Y may not be detected by this procedure.
Anser ADA measures serum adalimumab (ADA) levels and antibodies to adalimumab (ATA).
Anser IFX measures serum infliximab (IFX levels) and antibodies to infliximab (ATI).
Serum vedolizumab drug concentration and antibodies to vedolizumab levels
If ordering for transfuion of blood products refer to:
Type and Screen (except Neonates)
Neonate Transfusion (infants <4 months old)
ADB (Antideoxyribonuclease B), Anti-Dnase B, Antideoxyribonuclease, Antideoxyribonuclease B (ADB), DNA Streptococcal Antibody, DNase-B, Anti Streptococcal Antibodies, Serum ADNB
Apo A, ApoA-1, Apo A1, ApoA, ApoA-1, ApoA1, Apolipoprotein A, Apolipoprotein A-I, Apolipoprotein A1, Apolipoprotein AI
Apo B, APO-B, APOB, APOB-100, Apolipoprotein B-100
If total arsenic concentration is 10 mcg/L or greater, then speciation will be performed at an additional charge.
If indirect immunofluorescence assay (IFA) patterns suggest collapsin response-mediator protein (CRMP)-5-IgG, then CRMP-5-IgG Western blot is performed at an additional charge.
If IFA patterns suggest amphiphysin antibody, then amphiphysin antibody and/or amphiphysin immunoblot is performed at an additional charge.
If IFA pattern suggests antineuronal nuclear antibodies (ANNA)-1 antibody, then ANNA-1 and ANNA-2 immunoblot is performed at an additional charge.
If IFA pattern suggests Purkinje cytoplasmic antibody (PCA)-1 antibody, then PCA-1 immunoblot is performed at an additional charge.
If IFA pattern suggests PCA-Tr antibody, then PCA-Tr immunoblot is performed at an additional charge.
If IFA pattern suggests PCA type 1or type trace, then the appropriate antibody specific IFA is performed at an additional charge.
If IFA pattern suggests N-methyl-D-aspartate (NMDA)-receptor, then NMDA-receptor cell-binding assay (CBA) and NMDA-receptor titer are performed at an additional charge.
If IFA pattern suggests alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA)-receptor, then AMPA-receptor CBA and AMPA-receptor titer are performed at an additional charge.
If IFA pattern suggests gamma-aminobutyric acid B (GABA-B)-receptor, then GABA-B-receptor CBA and GABA-B-receptor titer are performed at an additional charge.
If IFA pattern suggests dipeptidyl-peptidase-like protein-6 antibody (DPPX) antibody, then DPPX antibody CBA and DPPX titer are performed at an additional charge.