Skip Ribbon Commands
Skip to main content
Sign In

26466 Antimicrobial Susceptibility, Aerobic Bacteria, Varies (ZMMLS)

Antimicrobial Susceptibility, Aerobic Bacteria, Varies (ZMMLS)
Test Code: ZMMLSSO
Synonyms/Keywords

​Antibiotic Susceptibility, Bacterial Susceptibility Testing, Extended Spectrum Beta-Lactamase (ESBL), MIC (Minimum Inhibitory Concentration), Minimum Inhibitory Concentration (MIC), Pneumococcus Susceptibility, Streptococcus pneumoniae Susceptibility, Susceptibility Testing, Amikacin, Amoxicillin, Amoxicillin-clavulanate, Ampicillin, Ampicillin-sulbactam, Azithromycin, Aztreonam, Cefaclor, Cefazolin, Cefdinir, Cefepime, Cefixime, Cefotaxime, Cefpodoxime, Ceftaroline, Ceftazidime, Ceftazidime-avibactam, Ceftolozane-tazobactam, Ceftriaxone, Chloramphenicol, Ciprofloxacin, Clarithromycin, Clindamycin, Colistin, Daptomycin, Doxycycline, Ertapenem, Erythromycin, Fosfomycin, Gentamicin, Imipenem, Levofloxacin, Linezolid, Meropenem, Metronidazole, Minocycline, Mupirocin, Nitrofurantoin, Ofloxacin, Oxacillin, Penicillin, Piperacillin, Piperacillin-tazobactam, Polymyxin, Quinupristin-dalfopristin, Rifampin, Sulfamethoxazole, Tedizolid, Tetracycline, Tigecycline, Tobramycin, Trimethoprim, Trimethoprim-sulfamethoxazole, Vancomycin, Achromobacter, Acinetobacter, Aeromonas, Aggregatibacter, Arcanobacterium, Arthrobacter, Bacillus, Brevibacillus, Brevibacterium, Brevundimonas, Burkholderia, Campylobacter, Cardiobacterium, Citrobacter, Cohnella, Coli, Corynebacterium, CRE, Cronobacter, Dermatobacter, Eikenella, Enterobacter, Enterococcus, Erysipelothrix, ESBL, Escherichia, Gemella, Gonorrhoeae, Gram negative, Gram positive, Haemophilus, Helicobacter, Klebsiella, Kingella, Lactobacillus, Lactococcus, Leifsonia, Leuconostoc, Listeria, Lysinibacillus, Meningitidis, MDR, MDRO, Microbacterium, MRSA, Moraxella, Neisseria, Ochrobactrum, Paenibacillus, Pandoraea, Pasteurella, Pediococcus, Pneumo, Pneumococcus, Proteus, Pseudomonas, Raoultella, Rothia, Salmonella, Serratia, Shewanella, Shigella, Sphingomonas, Sporolactobacillus, Staph, Staphylococcus, Stenotrophomonas, Strep, Streptococcus, Trueperella, Turicella, VISA, Vibrio, Viridans, VRE, Yersinia, Oerskovia, Avibactam-ceftazidime, Avycaz, Meropenem-vaborbactam, Sivextro, Vabormere, Zerbaxa, Lelliottia, Delafloxacin, Omadacycline, H pylori, H. pylori, mecA, Nuzyra, Abiotrophia, Cefiderocol, Colistin Agar Testing, Enterobacteriales, Granulicatella

Test Components

​When this test is ordered, the reflex tests may be performed at an additional charge.

All aerobically growing bacteria submitted will automatically have susceptibility testing performed and billed as appropriate. Antimicrobial agents appropriate to the organism and specimen source will be tested according to Mayo Clinic's practice and the laboratory's standard operating procedures.

If appropriate, testing for mecA will be performed by polymerase chain reaction (PCR) under MARP1 / mecA, Molecular Detection, PCR (Bill Only). Indications for mecA testing include inadequate growth by phenotypic antimicrobial susceptibility testing, lack of current organism breakpoints for oxacillin or cefoxitin, and assessment of discrepancies between cefoxitin and oxacillin phenotypic testing results.

In the event that an isolate of Helicobacter pylori does not grow from a client sample or does not grow for susceptibility testing, reflex testing for HPCR1 / Helicobacter pylori with Clarithromycin Resistance Prediction, Molecular Detection, PCR (Bill Only) may be added.

Mayo Clinic Laboratories will not perform susceptibility testing on select agents (eg, Bacillus anthracisBrucella species, Burkholderia malleiBurkholderia pseudomalleiFrancisella tularensis, and Yersinia pestis). Consult with your state health department or the CDC regarding antimicrobial susceptibility testing of such isolates.

Useful For

​Determining the in vitro susceptibility of aerobic bacteria involved in human infections.

Specimen Requirements
Specimen TypePreferred Container/TubeAcceptable Container/TubeSpecimen VolumeSpecimen Minimum Volume
(allows for 1 repeat)
Pediatric Minimum Volume
(no repeat)
​Organism in pure culture​Agar slant or other appropriate media
Collection Processing Instructions

​Organism identification and specimen source are required.

1. Perform isolation of infecting bacteria.

2. Organism must be in pure culture, actively growing. Do not submit mixed cultures.

Specimen Stability Information
Specimen TypeTemperature
​Varies ​ ​​Ambient (preferred)
​Frozen
​Refrigerated
Rejection Criteria
Agar plate
Interference

​In vitro susceptibility does not guarantee clinical response. Therefore, the decision to treat with a particular agent should not be based solely on the antimicrobial susceptibility testing result.

Performing Laboratory Information
Performing LocationDay(s) Test PerformedReport AvailableMethodology/Instrumentation
​Mayo Clinic Laboratories​Monday through Sunday​4 to 7 days​Minimal Inhibitory Concentration (MIC) (Agar Dilution or Broth Microdilution or Gradient Diffusion) or Disk Diffusion(if appropriate)
Reference Lab
Interpretation

A "susceptible" category result and a low minimum inhibitory concentration value indicate in vitro susceptibility of the organism to the antimicrobial tested.

Refer to Reference Values for interpretation of various antimicrobial susceptibility interpretive categories (ie, susceptible, susceptible-dose dependent, intermediate, nonsusceptible, resistant, or epidemiological cutoff value).

Outreach CPTs
CPTModifier
(if needed)
QuantityDescriptionComments
​87077​Ident by MALDI-TOF mass spec​if appropriate
​87185​Beta lactamase​if appropriate
​87186​Antimicrobial Susceptibility, Aerobic Bacteria, MIC - per organism for routine battery​if appropriate
​87181​Susceptibility per drug and per organism for drugs not in routine battery​if appropriate
​87150​H pylori + Claritho Resistance PCR​if appropriate
​87150​mecA PCR​if appropriate
Synonyms/Keywords

​Antibiotic Susceptibility, Bacterial Susceptibility Testing, Extended Spectrum Beta-Lactamase (ESBL), MIC (Minimum Inhibitory Concentration), Minimum Inhibitory Concentration (MIC), Pneumococcus Susceptibility, Streptococcus pneumoniae Susceptibility, Susceptibility Testing, Amikacin, Amoxicillin, Amoxicillin-clavulanate, Ampicillin, Ampicillin-sulbactam, Azithromycin, Aztreonam, Cefaclor, Cefazolin, Cefdinir, Cefepime, Cefixime, Cefotaxime, Cefpodoxime, Ceftaroline, Ceftazidime, Ceftazidime-avibactam, Ceftolozane-tazobactam, Ceftriaxone, Chloramphenicol, Ciprofloxacin, Clarithromycin, Clindamycin, Colistin, Daptomycin, Doxycycline, Ertapenem, Erythromycin, Fosfomycin, Gentamicin, Imipenem, Levofloxacin, Linezolid, Meropenem, Metronidazole, Minocycline, Mupirocin, Nitrofurantoin, Ofloxacin, Oxacillin, Penicillin, Piperacillin, Piperacillin-tazobactam, Polymyxin, Quinupristin-dalfopristin, Rifampin, Sulfamethoxazole, Tedizolid, Tetracycline, Tigecycline, Tobramycin, Trimethoprim, Trimethoprim-sulfamethoxazole, Vancomycin, Achromobacter, Acinetobacter, Aeromonas, Aggregatibacter, Arcanobacterium, Arthrobacter, Bacillus, Brevibacillus, Brevibacterium, Brevundimonas, Burkholderia, Campylobacter, Cardiobacterium, Citrobacter, Cohnella, Coli, Corynebacterium, CRE, Cronobacter, Dermatobacter, Eikenella, Enterobacter, Enterococcus, Erysipelothrix, ESBL, Escherichia, Gemella, Gonorrhoeae, Gram negative, Gram positive, Haemophilus, Helicobacter, Klebsiella, Kingella, Lactobacillus, Lactococcus, Leifsonia, Leuconostoc, Listeria, Lysinibacillus, Meningitidis, MDR, MDRO, Microbacterium, MRSA, Moraxella, Neisseria, Ochrobactrum, Paenibacillus, Pandoraea, Pasteurella, Pediococcus, Pneumo, Pneumococcus, Proteus, Pseudomonas, Raoultella, Rothia, Salmonella, Serratia, Shewanella, Shigella, Sphingomonas, Sporolactobacillus, Staph, Staphylococcus, Stenotrophomonas, Strep, Streptococcus, Trueperella, Turicella, VISA, Vibrio, Viridans, VRE, Yersinia, Oerskovia, Avibactam-ceftazidime, Avycaz, Meropenem-vaborbactam, Sivextro, Vabormere, Zerbaxa, Lelliottia, Delafloxacin, Omadacycline, H pylori, H. pylori, mecA, Nuzyra, Abiotrophia, Cefiderocol, Colistin Agar Testing, Enterobacteriales, Granulicatella

Test Components

​When this test is ordered, the reflex tests may be performed at an additional charge.

All aerobically growing bacteria submitted will automatically have susceptibility testing performed and billed as appropriate. Antimicrobial agents appropriate to the organism and specimen source will be tested according to Mayo Clinic's practice and the laboratory's standard operating procedures.

If appropriate, testing for mecA will be performed by polymerase chain reaction (PCR) under MARP1 / mecA, Molecular Detection, PCR (Bill Only). Indications for mecA testing include inadequate growth by phenotypic antimicrobial susceptibility testing, lack of current organism breakpoints for oxacillin or cefoxitin, and assessment of discrepancies between cefoxitin and oxacillin phenotypic testing results.

In the event that an isolate of Helicobacter pylori does not grow from a client sample or does not grow for susceptibility testing, reflex testing for HPCR1 / Helicobacter pylori with Clarithromycin Resistance Prediction, Molecular Detection, PCR (Bill Only) may be added.

Mayo Clinic Laboratories will not perform susceptibility testing on select agents (eg, Bacillus anthracisBrucella species, Burkholderia malleiBurkholderia pseudomalleiFrancisella tularensis, and Yersinia pestis). Consult with your state health department or the CDC regarding antimicrobial susceptibility testing of such isolates.

Ordering Applications
Ordering ApplicationDescription
​COM​Antimicrobial Susceptibility, Aerobic, MIC (ZMMLS)
​Cerner​Antimicrobial Susceptibility, Aerobic Bacteria, MIC (ZMMLS)
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
Specimen TypePreferred Container/TubeAcceptable Container/TubeSpecimen VolumeSpecimen Minimum Volume
(allows for 1 repeat)
Pediatric Minimum Volume
(no repeat)
​Organism in pure culture​Agar slant or other appropriate media
Collection Processing

​Organism identification and specimen source are required.

1. Perform isolation of infecting bacteria.

2. Organism must be in pure culture, actively growing. Do not submit mixed cultures.

Specimen Stability Information
Specimen TypeTemperature
​Varies ​ ​​Ambient (preferred)
​Frozen
​Refrigerated
Rejection Criteria
Agar plate
Interference

​In vitro susceptibility does not guarantee clinical response. Therefore, the decision to treat with a particular agent should not be based solely on the antimicrobial susceptibility testing result.

Useful For

​Determining the in vitro susceptibility of aerobic bacteria involved in human infections.

Test Components

​When this test is ordered, the reflex tests may be performed at an additional charge.

All aerobically growing bacteria submitted will automatically have susceptibility testing performed and billed as appropriate. Antimicrobial agents appropriate to the organism and specimen source will be tested according to Mayo Clinic's practice and the laboratory's standard operating procedures.

If appropriate, testing for mecA will be performed by polymerase chain reaction (PCR) under MARP1 / mecA, Molecular Detection, PCR (Bill Only). Indications for mecA testing include inadequate growth by phenotypic antimicrobial susceptibility testing, lack of current organism breakpoints for oxacillin or cefoxitin, and assessment of discrepancies between cefoxitin and oxacillin phenotypic testing results.

In the event that an isolate of Helicobacter pylori does not grow from a client sample or does not grow for susceptibility testing, reflex testing for HPCR1 / Helicobacter pylori with Clarithromycin Resistance Prediction, Molecular Detection, PCR (Bill Only) may be added.

Mayo Clinic Laboratories will not perform susceptibility testing on select agents (eg, Bacillus anthracisBrucella species, Burkholderia malleiBurkholderia pseudomalleiFrancisella tularensis, and Yersinia pestis). Consult with your state health department or the CDC regarding antimicrobial susceptibility testing of such isolates.

Interpretation

A "susceptible" category result and a low minimum inhibitory concentration value indicate in vitro susceptibility of the organism to the antimicrobial tested.

Refer to Reference Values for interpretation of various antimicrobial susceptibility interpretive categories (ie, susceptible, susceptible-dose dependent, intermediate, nonsusceptible, resistant, or epidemiological cutoff value).

For more information visit:
Performing Laboratory Information
Performing LocationDay(s) Test PerformedReport AvailableMethodology/Instrumentation
​Mayo Clinic Laboratories​Monday through Sunday​4 to 7 days​Minimal Inhibitory Concentration (MIC) (Agar Dilution or Broth Microdilution or Gradient Diffusion) or Disk Diffusion(if appropriate)
Reference Lab
For billing questions, see Contacts
Outreach CPTs
CPTModifier
(if needed)
QuantityDescriptionComments
​87077​Ident by MALDI-TOF mass spec​if appropriate
​87185​Beta lactamase​if appropriate
​87186​Antimicrobial Susceptibility, Aerobic Bacteria, MIC - per organism for routine battery​if appropriate
​87181​Susceptibility per drug and per organism for drugs not in routine battery​if appropriate
​87150​H pylori + Claritho Resistance PCR​if appropriate
​87150​mecA PCR​if appropriate
For most current information refer to the Marshfield Laboratory online reference manual.