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26039 Allergen Panel, Respiratory Midwest (RPR8)

Allergen Panel, Respiratory Midwest (RPR8)
Test Code: ALRP8SO
Synonyms/Keywords
 
Immunoglobulin E (IgE), S
 
 
 
House Dust Mites/D.P., IgE
 
 
 
House Dust Mites/D.F., IgE
 
 
 
Cat Epithelium, IgE
 
 
 
Dog Dander, IgE
 
 
 
Bermuda Grass, IgE
 
 
 
Timothy Grass, IgE
 
 
 
Cockroach, IgE
 
 
 
Penicillium, IgE
 
 
 
Cladosporium, IgE
 
 
 
Aspergillus Fumigatus, IgE
 
 
 
Alternaria Tenuis, IgE
 
 
 
Box Eld/Maple, S, IgE
 
 
 
Mountain Cedar, IgE
 
 
 
Oak, IgE
 
 
 
Elm, IgE
 
 
 
Walnut Tree, IgE
 
 
 
Eastern Sycamore, IgE
 
 
 
Cottonwood, IgE
 
 
 
White Ash, IgE
 
 
 
Pecan Hickory, IgE
 
 
 
Mulberry, IgE
 
 
 
Short Ragweed, IgE
 
 
 
Russian Thistle, IgE
 
 
 
Rough Pigweed, IgE
 
 
 
Rough Marsh Elder, IgE
 
Useful For

Assessing sensitization to various inhalant allergens commonly found in the Central Midwest region including Iowa, Illinois and Missouri

Defining the allergen responsible for eliciting signs and symptoms

Identifying allergens:

-Responsible for allergic disease and/or anaphylactic episode

-To confirm sensitization prior to beginning immunotherapy

-To investigate the specificity of allergic reactions to insect venom allergens, drugs, or chemical allergens

Specimen Requirements
Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)
Pediatric Minimum Volume
(no repeat)
​No ​Serum ​Red Top Tube (RTT) ​Serum Separator Tube (SST) ​2 mL ​1.55 mL
Specimen Stability Information
Specimen Type Temperature Time
​Serum ​ ​Refrigerate ​14 days
​Frozen ​90 days
Interference

An elevated concentration of total IgE is not diagnostic for allergic disease, and must be interpreted in the clinical context of the patient, including age, gender, travel history, potential allergen exposure, and family history.

A normal concentration of total IgE does not eliminate the possibility of allergic disease. In patients with a high index of suspicion for allergic disease, testing for allergen-specific IgEs may be warranted.

Testing for allergen-specific IgE antibodies is not useful in patients previously treated with immunotherapy to determine if residual clinical sensitivity exists, or in patients in whom the medical management does not depend upon identification of allergen specificity.

Some individuals with clinically insignificant sensitivity to allergens may have measurable levels of IgE antibodies in serum, and results must be interpreted in the clinical context.

False-positive results for IgE antibodies may occur in patients with markedly elevated serum IgE (>2500 kU/L) due to nonspecific binding to allergen solid phases.

Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
​Mayo Clinic Laboratories ​Monday through Saturday ​1 day ​Fluorescence Enzyme Immunoassay (FEIA)
Reference Lab
Reference Range Information
Specific IgE:
Class
IgE kU/L
Interpretation
0
<0.35
Negative
1
0.35-0.69
Equivocal
2
0.70-3.49
Positive
3
3.50-17.4
Positive
4
17.5-49.9
Strongly positive
5
50.0-99.9
Strongly positive
6
> or =100
Strongly positive
Reference values apply to all ages.
 
Total IgE:
Results Reported in kU/L
Age
Reference interval
0-5 months
< or =13
6-11 months
< or =34
1 and 2 years
< or =97
3 years
< or =199
4-6 years
< or =307
7 and 8 years
< or =403
9-12 years
< or =696
13-15 years
< or =629
16 and 17 years
< or =537
18 years and older
< or =214
Interpretation
Elevated concentrations of total IgE may be found in a variety of clinical diseases, including allergic disease, certain primary immunodeficiencies, infections, inflammatory diseases, and malignancies.
 
Detection of allergen-specific IgE antibodies in serum (Class 1 or greater) indicates an increased likelihood of allergic disease as opposed to other etiologies and defines the allergens that may be responsible for eliciting signs and symptoms.
Outreach CPTs
CPT Modifier
(if needed)
Quantity Description Comments
​82785 ​1 ​IgE
​86003 ​25 ​Each indivual allergen
Synonyms/Keywords
 
Immunoglobulin E (IgE), S
 
 
 
House Dust Mites/D.P., IgE
 
 
 
House Dust Mites/D.F., IgE
 
 
 
Cat Epithelium, IgE
 
 
 
Dog Dander, IgE
 
 
 
Bermuda Grass, IgE
 
 
 
Timothy Grass, IgE
 
 
 
Cockroach, IgE
 
 
 
Penicillium, IgE
 
 
 
Cladosporium, IgE
 
 
 
Aspergillus Fumigatus, IgE
 
 
 
Alternaria Tenuis, IgE
 
 
 
Box Eld/Maple, S, IgE
 
 
 
Mountain Cedar, IgE
 
 
 
Oak, IgE
 
 
 
Elm, IgE
 
 
 
Walnut Tree, IgE
 
 
 
Eastern Sycamore, IgE
 
 
 
Cottonwood, IgE
 
 
 
White Ash, IgE
 
 
 
Pecan Hickory, IgE
 
 
 
Mulberry, IgE
 
 
 
Short Ragweed, IgE
 
 
 
Russian Thistle, IgE
 
 
 
Rough Pigweed, IgE
 
 
 
Rough Marsh Elder, IgE
 
Ordering Applications
Ordering Application Description
Centricity Respiratory P, Region 8, Central Midwest (RPR8)
​Cerner Respiratory P, Region 8, Central Midwest (RPR8)
​COM Respiratory P, Region 8, Central Midwest (RPR8)
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)
Pediatric Minimum Volume
(no repeat)
​No ​Serum ​Red Top Tube (RTT) ​Serum Separator Tube (SST) ​2 mL ​1.55 mL
Specimen Stability Information
Specimen Type Temperature Time
​Serum ​ ​Refrigerate ​14 days
​Frozen ​90 days
Interference

An elevated concentration of total IgE is not diagnostic for allergic disease, and must be interpreted in the clinical context of the patient, including age, gender, travel history, potential allergen exposure, and family history.

A normal concentration of total IgE does not eliminate the possibility of allergic disease. In patients with a high index of suspicion for allergic disease, testing for allergen-specific IgEs may be warranted.

Testing for allergen-specific IgE antibodies is not useful in patients previously treated with immunotherapy to determine if residual clinical sensitivity exists, or in patients in whom the medical management does not depend upon identification of allergen specificity.

Some individuals with clinically insignificant sensitivity to allergens may have measurable levels of IgE antibodies in serum, and results must be interpreted in the clinical context.

False-positive results for IgE antibodies may occur in patients with markedly elevated serum IgE (>2500 kU/L) due to nonspecific binding to allergen solid phases.

Useful For

Assessing sensitization to various inhalant allergens commonly found in the Central Midwest region including Iowa, Illinois and Missouri

Defining the allergen responsible for eliciting signs and symptoms

Identifying allergens:

-Responsible for allergic disease and/or anaphylactic episode

-To confirm sensitization prior to beginning immunotherapy

-To investigate the specificity of allergic reactions to insect venom allergens, drugs, or chemical allergens

Reference Range Information
Specific IgE:
Class
IgE kU/L
Interpretation
0
<0.35
Negative
1
0.35-0.69
Equivocal
2
0.70-3.49
Positive
3
3.50-17.4
Positive
4
17.5-49.9
Strongly positive
5
50.0-99.9
Strongly positive
6
> or =100
Strongly positive
Reference values apply to all ages.
 
Total IgE:
Results Reported in kU/L
Age
Reference interval
0-5 months
< or =13
6-11 months
< or =34
1 and 2 years
< or =97
3 years
< or =199
4-6 years
< or =307
7 and 8 years
< or =403
9-12 years
< or =696
13-15 years
< or =629
16 and 17 years
< or =537
18 years and older
< or =214
Interpretation
Elevated concentrations of total IgE may be found in a variety of clinical diseases, including allergic disease, certain primary immunodeficiencies, infections, inflammatory diseases, and malignancies.
 
Detection of allergen-specific IgE antibodies in serum (Class 1 or greater) indicates an increased likelihood of allergic disease as opposed to other etiologies and defines the allergens that may be responsible for eliciting signs and symptoms.
For more information visit:
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
​Mayo Clinic Laboratories ​Monday through Saturday ​1 day ​Fluorescence Enzyme Immunoassay (FEIA)
Reference Lab
For billing questions, see Contacts
Outreach CPTs
CPT Modifier
(if needed)
Quantity Description Comments
​82785 ​1 ​IgE
​86003 ​25 ​Each indivual allergen
For most current information refer to the Marshfield Laboratory online reference manual.