Anora Miscarriage Test for Products of Conception (POC)

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Test Code: MISC

Overview
Ordering
Specimen
Performing
Clinical/Interpretive
Contacts
Coding

Useful For

To determine if a chromosomal abnormality was the likely cause of miscarriage.

Specimen Requirements

Fasting Required	Specimen Type	Preferred Container/Tube	Acceptable Container/Tube	Specimen Volume	Specimen Minimum Volume (allows for 1 repeat)
No	Blood	EDTA Lavender Top Tube (LTT)		6 mL	5 mL
No	Tissue (chorionic vill, gestational sac, fetal skin/tissue, umbilical cord tissue or cytogenetic tissue cell pellets)	Sterile Container - provided with kit			0.5 mm

Collection Processing Instructions

**ANORA TESTING IS FOR BEAVER DAM CLIENTS ONLY**

Use Anora kit.

The blood sample is helpful to rule out maternal cell contamination. Tissue and patient samples should be placed in saline, not formalin, and they should be shipped to Natera as soon as possible. Tissue samples should be stored in the refrigerator (not frozen) until the next shipping day. The blood tube (EDTA purple top tube) can also be stored in the refrigerator until shipping. Ship at ambient temperature, blood and tissue. DO NOT freeze.

Tissue collection tip:

Separate chorionic villi from blood clots and decidua to include only chorionic villi to reduce chance of maternal cell contamination. Refer to tissue sorting and sample collection instructions included in the kit. Sorting samples is however not required.

Cord blood samples should be drawn into an EDTA (LTT), and the tube should be labeled as "cord/fetal blood". Cord tissue or fetal skin can be placed in the saline POC cup provided with the Anora kit.

Specimen Stability Information

Specimen Type	Temperature	Time
Blood	Refrigerated	14 days
Tissue	Refrigerated	30 days

Rejection Criteria

POC samples sent more than 30 days after collection and parental blood samples sent more than 14 days after collection cannot be accepted.

Tissue and patient samples should be placed in saline, NOT formalin.

Interference

Anora cannot detect balanced chromosome rearragements (Inversions or balanced translocations). Balanced rearrangements are not a cause of miscarriage, but they can be incidental findings on traditional karyotypes.

Performing Laboratory Information

Performing Location	Day(s) Test Performed	Analytical Time	Methodology/Instrumentation
Natera, Inc.	Monday through Friday	7 days	Single Nucleotide Polymorphism (SNP) microarray

Reference Lab

Natera, Inc.

Reference Range Information

An interpretive report will be provided.

Interpretation

An interpretive report will be provided.

Ordering Applications

Ordering Application	Description

If the ordering application you are looking for is not listed, contact your local laboratory for assistance.

Specimen Requirements

Fasting Required	Specimen Type	Preferred Container/Tube	Acceptable Container/Tube	Specimen Volume	Specimen Minimum Volume (allows for 1 repeat)
No	Blood	EDTA Lavender Top Tube (LTT)		6 mL	5 mL
No	Tissue (chorionic vill, gestational sac, fetal skin/tissue, umbilical cord tissue or cytogenetic tissue cell pellets)	Sterile Container - provided with kit			0.5 mm

Collection Processing

**ANORA TESTING IS FOR BEAVER DAM CLIENTS ONLY**

Use Anora kit.

Tissue collection tip:

Separate chorionic villi from blood clots and decidua to include only chorionic villi to reduce chance of maternal cell contamination. Refer to tissue sorting and sample collection instructions included in the kit. Sorting samples is however not required.

Cord blood samples should be drawn into an EDTA (LTT), and the tube should be labeled as "cord/fetal blood". Cord tissue or fetal skin can be placed in the saline POC cup provided with the Anora kit.

Specimen Stability Information

Specimen Type	Temperature	Time
Blood	Refrigerated	14 days
Tissue	Refrigerated	30 days

Rejection Criteria

POC samples sent more than 30 days after collection and parental blood samples sent more than 14 days after collection cannot be accepted.

Tissue and patient samples should be placed in saline, NOT formalin.

Interference

Useful For

To determine if a chromosomal abnormality was the likely cause of miscarriage.

Reference Range Information

An interpretive report will be provided.

Interpretation

An interpretive report will be provided.

For more information visit:

http://labtestsonline.org

Performing Laboratory Information

Performing Location	Day(s) Test Performed	Analytical Time	Methodology/Instrumentation
Natera, Inc.	Monday through Friday	7 days	Single Nucleotide Polymorphism (SNP) microarray

Reference Lab

Natera, Inc.

For billing questions, see Contacts

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For most current information refer to the Marshfield Laboratory online reference manual.

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Tissue collection tip:​​

Separate chorionic villi from blood clots and decidua to include only chorionic villi to reduce chance of maternal cell contamination. Refer to tissue sorting and sample collection instructions included in the kit. Sorting samples is however not required.

Tissue collection tip:​​

Separate chorionic villi from blood clots and decidua to include only chorionic villi to reduce chance of maternal cell contamination. Refer to tissue sorting and sample collection instructions included in the kit. Sorting samples is however not required.

26579 Anora Miscarriage Test for Products of Conception (POC)

Tissue collection tip:

Tissue collection tip: