Test orders a baseline cortisol plus one 60 min post-ACTH cortisol. n alternative Low Dose (1 ug) ACTH Stimulation Test is also employed by some members of the Endocrinology Department. This requires saline dilution of a 250 ug dose as a 1 ug dosage form is not yet commercially available. Some argue that this dosing level is more physiologic and provides a better indication of adrenal reserve. For this protocol, a 30-minute specimen is typically obtained following injection. A normal response with this protocol is any cortisol >= 18 ug/dL.
ACTH (Cosyntrophin) One-Hour Stimulation Test