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26159 Apolipoprotein B, Plasma (APLB)

Apolipoprotein B, Plasma (APLB)
Test Code: APLBSO
Useful For

Assessment of residual risk in patients at target non high-density lipoprotein­ cholesterol (HDL-C) (or low-density lipoprotein-cholesterol: LDL-C); Follow-up studies in individuals with non-HDL-C (or LDL-C) values inconsistent with risk factors or clinical presentation; Definitive studies of cardiac risk factors in individuals with significant family histories of coronary artery disease or other increased risk factors; Confirmation of suspected abetalipoproteinemia or hypobetalipoproteinemia

Specimen Requirements
Fasting RequiredSpecimen TypePreferred Container/TubeAcceptable Container/TubeSpecimen VolumeSpecimen Minimum Volume
(allows for 1 repeat)
Pediatric Minimum Volume
(no repeat)
​No​EDTA Plasma​Lavender Top Tube (LTT)​1 mL​0.5 mL
Collection Processing Instructions

​Centrifuge and aliquot 1 ml of plasma. Send refrigerated.

Specimen Stability Information
Specimen TypeTemperatureTime
​Plasma EDTA ​​Refrigerate (preferred)​8 days
​Frozen​60 days
Rejection Criteria
Grossly Hemolyzed
​Grossly Icteric
Performing Laboratory Information
Performing LocationDay(s) Test PerformedAnalytical TimeMethodology/Instrumentation
​Mayo Clinic Laboratories​Monday through Saturday​2 days​Immunoturbidimetric Assay
Reference Lab
Reference Range Information
Performing LocationReference Range
​Mayo Clinic Laboratories

<24 months: not established

2-17 years:      

       Acceptable: <90 mg/dl

       Borderline high: 90-109 mg/dl

       High: >=110 mg/dl

>18 years:         

       Desirable: <90 mg/dl Above Desirable: 90-99 mg/dl Borderline  high:  100-119 mg/dl

       High: 120-139 mg/dl

       Very high: >=140 mg/dl

Interpretation

Elevated ApoB confers increased risk of coronary artery disease ApoB can be used as a therapeutic target analogous to non-HDL-C and LDL-C.

Risk Category

Therapeutic Target:  ApoB          Non-HDL-C LDL-C

Moderate to High: < 90 mg/dl <130 mg/dl <100 mg/dl

Very High:              <80 mg/dl <100 mg/dl <70 mg/dl 

Extremely low values of ApoB (<48 mg/dl) are related to malabsorption of food lipids and can lead to polyneuropathy.

Outreach CPTs
CPTModifier
(if needed)
QuantityDescriptionComments
​82172​1
Ordering Applications
Ordering ApplicationDescription
​Cerner​Apolipoprotein B, Plasma (APLB)
​COM​Apolipoprotein B, Plasma (APLB)
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
Fasting RequiredSpecimen TypePreferred Container/TubeAcceptable Container/TubeSpecimen VolumeSpecimen Minimum Volume
(allows for 1 repeat)
Pediatric Minimum Volume
(no repeat)
​No​EDTA Plasma​Lavender Top Tube (LTT)​1 mL​0.5 mL
Collection Processing

​Centrifuge and aliquot 1 ml of plasma. Send refrigerated.

Specimen Stability Information
Specimen TypeTemperatureTime
​Plasma EDTA ​​Refrigerate (preferred)​8 days
​Frozen​60 days
Rejection Criteria
Grossly Hemolyzed
​Grossly Icteric
Useful For

Assessment of residual risk in patients at target non high-density lipoprotein­ cholesterol (HDL-C) (or low-density lipoprotein-cholesterol: LDL-C); Follow-up studies in individuals with non-HDL-C (or LDL-C) values inconsistent with risk factors or clinical presentation; Definitive studies of cardiac risk factors in individuals with significant family histories of coronary artery disease or other increased risk factors; Confirmation of suspected abetalipoproteinemia or hypobetalipoproteinemia

Reference Range Information
Performing LocationReference Range
​Mayo Clinic Laboratories

<24 months: not established

2-17 years:      

       Acceptable: <90 mg/dl

       Borderline high: 90-109 mg/dl

       High: >=110 mg/dl

>18 years:         

       Desirable: <90 mg/dl Above Desirable: 90-99 mg/dl Borderline  high:  100-119 mg/dl

       High: 120-139 mg/dl

       Very high: >=140 mg/dl

Interpretation

Elevated ApoB confers increased risk of coronary artery disease ApoB can be used as a therapeutic target analogous to non-HDL-C and LDL-C.

Risk Category

Therapeutic Target:  ApoB          Non-HDL-C LDL-C

Moderate to High: < 90 mg/dl <130 mg/dl <100 mg/dl

Very High:              <80 mg/dl <100 mg/dl <70 mg/dl 

Extremely low values of ApoB (<48 mg/dl) are related to malabsorption of food lipids and can lead to polyneuropathy.

For more information visit:
Performing Laboratory Information
Performing LocationDay(s) Test PerformedAnalytical TimeMethodology/Instrumentation
​Mayo Clinic Laboratories​Monday through Saturday​2 days​Immunoturbidimetric Assay
Reference Lab
For billing questions, see Contacts
Outreach CPTs
CPTModifier
(if needed)
QuantityDescriptionComments
​82172​1
For most current information refer to the Marshfield Laboratory online reference manual.