Apo B, APO-B, APOB, APOB-100, Apolipoprotein B-100
Assessment of cardiovascular risk
Follow-up studies in individuals with non-HDL-C (or LDL-C)
values inconsistent with risk factors or clinical presentation
Definitive studies of cardiac
risk factors in individuals with
significant family histories
of coronary artery disease or other increased risk factors
suspected abetalipoproteinemia or hypobetalipoproteinemia
Centrifuge and aliquot 1 ml of serum.
In very rare cases, gammopathy, in particular type IgM (Waldenstrom macroglobulinemia), may cause unreliable results.
<24 months: not established
Acceptable: <90 mg/dl
Borderline high: 90-109 mg/dl
High: >=110 mg/dl
Desirable: <90 mg/dl
Above Desirable: 90-99 mg/dl
Borderline high: 100-119 mg/dl
High: 120-139 mg/dl
Very high: >=140 mg/dl
Elevated ApoB confers increased risk of atherosclerotic cardiovascular disease, even in a context of acceptable LDL cholesterol.
Extremely low values of ApoB (<48 mg/dl) are related to malabsorption of food lipids and can lead to polyneuropathy.