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26688 Meningitis/Encephalitis Panel, NAT, Spinal Fluid

Meningitis/Encephalitis Panel, NAT, Spinal Fluid
Test Code: MEPNAT
Synonyms/Keywords

​Encephalitis, meningitis, Escherichia coli k1, Haemophilus inlfuenza, Listeria monocytogenes, Neisseria meningitidis, Streptococcus agalactiae, Streptococcus pneumoniae, cytomegalovirus, enterovirus, varicella zoster virus, herpes simplex virus, human Parechovirus, Cryptococcus neoformans/gatti ​​​

Useful For

​The simultaneous detection and identification of multiple bacterial, viral, and yeast nucleic acids directly from cerebrospinal fluid (CSF) specimens obtained via lumbar puncture from individuals with signs and/or symptoms of meningitis and/or encephalitis.

The results of this test should not be used as the sole basis for diagnosis, treatment, or other management decisions.

This test is not intended for use with cerebrospinal fluid (CSF) collected from indwelling medical devices (e.g., CSF shunts).

Targets Detected:

Bacteria:Viruses:Yeast:
  • Escherichia coli K1
  • Cytomegalovirus
  • Cryptococcus neoformans/gattii
  • Haemophilus influenzae
  • Enterovirus
 
  • Listeria monocytogenes
  • Herpes simplex virus 1
 
  • Neisseria meningitidis
  • Herpes simplex virus 2
 
  • Streptococcus agalactiae
  • Human herpesvirus 6
 
  • Streptococcus pneumoniae
  • Human parechovirus
 
 
  • Varicella zoster virus
 

​

Specimen Requirements
Fasting RequiredSpecimen TypePreferred Container/TubeAcceptable Container/TubeSpecimen VolumeSpecimen Minimum Volume
(allows for 1 repeat)		Pediatric Minimum Volume
(no repeat)

​No
​CSF
​Sterile, leak-proof vial
​

​1.0 mL
​0.5 mL
​
Collection Processing Instructions

​For more information on Specimen Collection Media/Swab, see Specimen Transport Pictorial ​​

Specimen Stability Information
Specimen TypeTemperatureTime

​CSF​​
​Refrigerated
​7 days
​Frozen
​30 days
Rejection Criteria

Specimens in transport media

Centrifuged specimens

Fluids collected from a CSF shunt

Performing Laboratory Information
Performing LocationDay(s) Test PerformedAnalytical TimeMethodology/Instrumentation
Marshfield​
​Monday through Sunday
​4 hours
​Multiplex-PCR
Test Information

​

  1. It is recommended that the following test be ordered with this test:
    • CSF Fluid Panel; CSF Profile
    • Culture, Aerobic- with Susceptibilities; AERS
  2. If clinically indicated, it recommended the following tests be ordered with this test:
    • Culture, Fungus- General; FUNG
    • Cryptococcus Antigen Screen with Titer, CSF; CRYPAGC

Reference Range Information
Performing LocationReference Range
​Marshfield
​​Not Detected 
Outreach CPTs
CPTModifier
(if needed)		QuantityDescriptionComments
87483​
​​​​Infectious agent detection by nucleic acid; central nervous system pathogen includes multiplex reverse transcription, when performed, and multiplex amplified probe technique, multiple types, or subtypes, 12-25 targets​
​
Synonyms/Keywords

​Encephalitis, meningitis, Escherichia coli k1, Haemophilus inlfuenza, Listeria monocytogenes, Neisseria meningitidis, Streptococcus agalactiae, Streptococcus pneumoniae, cytomegalovirus, enterovirus, varicella zoster virus, herpes simplex virus, human Parechovirus, Cryptococcus neoformans/gatti ​​​

Ordering Applications
Ordering ApplicationDescription
​Cerner​
​Meningitis/Encephalitis Panel by Nucleic Acid Amplified Test​
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
Fasting RequiredSpecimen TypePreferred Container/TubeAcceptable Container/TubeSpecimen VolumeSpecimen Minimum Volume
(allows for 1 repeat)		Pediatric Minimum Volume
(no repeat)

​No
​CSF
​Sterile, leak-proof vial
​

​1.0 mL
​0.5 mL
​
Collection Processing

​For more information on Specimen Collection Media/Swab, see Specimen Transport Pictorial ​​

Specimen Stability Information
Specimen TypeTemperatureTime

​CSF​​
​Refrigerated
​7 days
​Frozen
​30 days
Rejection Criteria

Specimens in transport media

Centrifuged specimens

Fluids collected from a CSF shunt

Useful For

​The simultaneous detection and identification of multiple bacterial, viral, and yeast nucleic acids directly from cerebrospinal fluid (CSF) specimens obtained via lumbar puncture from individuals with signs and/or symptoms of meningitis and/or encephalitis.

The results of this test should not be used as the sole basis for diagnosis, treatment, or other management decisions.

This test is not intended for use with cerebrospinal fluid (CSF) collected from indwelling medical devices (e.g., CSF shunts).

Targets Detected:

Bacteria:Viruses:Yeast:
  • Escherichia coli K1
  • Cytomegalovirus
  • Cryptococcus neoformans/gattii
  • Haemophilus influenzae
  • Enterovirus
 
  • Listeria monocytogenes
  • Herpes simplex virus 1
 
  • Neisseria meningitidis
  • Herpes simplex virus 2
 
  • Streptococcus agalactiae
  • Human herpesvirus 6
 
  • Streptococcus pneumoniae
  • Human parechovirus
 
 
  • Varicella zoster virus
 

​

Reference Range Information
Performing LocationReference Range
​Marshfield
​​Not Detected 
For more information visit:
Performing Laboratory Information
Performing LocationDay(s) Test PerformedAnalytical TimeMethodology/Instrumentation
Marshfield​
​Monday through Sunday
​4 hours
​Multiplex-PCR
For billing questions, see Contacts
Outreach CPTs
CPTModifier
(if needed)		QuantityDescriptionComments
87483​
​​​​Infectious agent detection by nucleic acid; central nervous system pathogen includes multiplex reverse transcription, when performed, and multiplex amplified probe technique, multiple types, or subtypes, 12-25 targets​
​
For most current information refer to the Marshfield Laboratory online reference manual.