SMRNP, ENA, Extractable Nuclear Antibodies, RNP
RNP and SmRNP Antibodies
A confirmatory test for the evaluation of patients with signs and symptoms of MCTD and SLE. Anti-RNP antibodies include RNP and SmRNP. Frequently associated with nuclear coarse speckled patterns by ANA IFA.
Negative <1.0 AI
Analytical measuring range is 0.2-8.0 AI (Antibody Index)
Positive result(s) support diagnosis of mixed connective tissue disease, which resembles SLE but is not accompanied by renal involvement.