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# A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Ureaplasma species, PCR (URRP)
Test Code: URRPSO
Synonyms/Keywords
Ureaplasma urealyticum, Ureaplasma parvum, PCR
Useful For
Detection of Ureaplasma urealyticum and U parvum from urogenital, bone and joint, and lower respiratory sources.
Specimen Requirements
Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)
Pediatric Minimum Volume
(no repeat)
​Urogenital, Vaginal, Cervix, Urethra ​M6 Transport Media ​M4 or M5 Transport Media or Swab in Transport Media ​One swab ​One swab
​Fluids, Amniotic, Pelvic, Prostatic, Semen ​Sterile, screw-capped container ​M4, M5 or M6 Transport Media ​1-10 mL ​1 mL
​Urine ​Sterile, screw-capped container ​10 mL ​2 mL
​Sputum, Tracheal Secretions, Bronchial wash or lavage, Lung Fluid; or Nasal washings (only infants <3 months) ​Sterile, screw-capped container ​​M4, M5 or M6 Transport Media ​1-2 mL ​1 mL
​Synovial Fluid ​​Sterile, screw-capped container ​EDTA tube ​1 mL
​Tissue ​​Sterile, screw-capped container ​5 mm
Collection Processing Instructions

Specimens should be delivered to the laboratory as soon as possible.

Do not use calcium alginate or wooden shaft swabs.

Samples should be taken without contact with antiseptics or lubricants.

For more information on Specimen Collection Media/Swab, see Specimen Transport Pictorial.

Specimen Stability Information
Specimen Type Temperature Time
​M4, M5, M6 Transport Media ​ ​Refrigerate (preferred ​7 days
​Frozen ​7 days
​All other specimens ​Refrigerate ​7 days
Rejection Criteria
Cotton or calcium alginate-tipped swab, wooden shaft swab, dry swabs, swab containing gel or charcoal
​Formalin-fixed and/or paraffin-embedded tissues
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
​Mayo Medical Laboratories ​Monday through Friday ​3 days Real-Time Polymerase Chain Reaction (PCR) Using LightCycler and Fluorescent Resonance Energy Transfer (FRET)
Reference Lab
Test Information
Ureaplasma urealyticum and U parvum have been associated with a number of clinically significant infections, although their clinical significance may not always be clear as they are part of the normal genital flora. U urealyticum and U parvum have been associated with urethritis and epididymitis. They may cause upper urinary tract infection and they have been associated with infected renal stones. U urealyticum and U parvum may be isolated from amniotic fluid of women with preterm labor, premature rupture of membranes, spontaneous term labor, or chorioamnionitis. They may also cause neonatal infections, including meningoencephalitis and pneumonia. In addition, U urealyticum and U parvum have been reported to cause unusual infections, such as prosthetic joint infection and infections in transplant recipients.
 
Culture of Ureaplasma species is laborious, requiring a high degree of technical skill and taking several days. PCR detection is sensitive, specific, and provides same-day results. In addition, PCR allows the differentiation of U urealyticum and U parvum, which is not easily accomplished with culture. PCR assay has replaced conventional culture for U urealyticum and U parvum due to its speed and equivalent performance to culture.
Reference Range Information
Performing Location Reference Range
​Mayo Medical Laboratories ​Negative
Interpretation
A positive PCR result for the presence of a specific sequence found within the Ureaplasma urealyticum and U parvum ureC gene indicates the presence of U urealyticum or U parvum DNA in the specimen.
 
A negative PCR result indicates the absence of detectable U urealyticum and U parvum DNA in the specimen, but does not rule-out infection as false-negative results may occur due to inhibition of PCR, sequence variability underlying the primers and probes, or the presence of U urealyticum or U parvum in quantities less than the limit of detection of the assay.
Outreach CPTs
CPT Modifier
(if needed)
Quantity Description Comments
​87798 ​2
Synonyms/Keywords
Ureaplasma urealyticum, Ureaplasma parvum, PCR
Ordering Applications
Ordering Application Description
​Centricity Ureaplasma species, PCR (URRP)
​Cerner Ureaplasma species, PCR (URRP)
​COM Ureaplasma species, PCR (URRP)
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)
Pediatric Minimum Volume
(no repeat)
​Urogenital, Vaginal, Cervix, Urethra ​M6 Transport Media ​M4 or M5 Transport Media or Swab in Transport Media ​One swab ​One swab
​Fluids, Amniotic, Pelvic, Prostatic, Semen ​Sterile, screw-capped container ​M4, M5 or M6 Transport Media ​1-10 mL ​1 mL
​Urine ​Sterile, screw-capped container ​10 mL ​2 mL
​Sputum, Tracheal Secretions, Bronchial wash or lavage, Lung Fluid; or Nasal washings (only infants <3 months) ​Sterile, screw-capped container ​​M4, M5 or M6 Transport Media ​1-2 mL ​1 mL
​Synovial Fluid ​​Sterile, screw-capped container ​EDTA tube ​1 mL
​Tissue ​​Sterile, screw-capped container ​5 mm
Collection Processing Instructions

Specimens should be delivered to the laboratory as soon as possible.

Do not use calcium alginate or wooden shaft swabs.

Samples should be taken without contact with antiseptics or lubricants.

For more information on Specimen Collection Media/Swab, see Specimen Transport Pictorial.

Specimen Stability Information
Specimen Type Temperature Time
​M4, M5, M6 Transport Media ​ ​Refrigerate (preferred ​7 days
​Frozen ​7 days
​All other specimens ​Refrigerate ​7 days
Rejection Criteria
Cotton or calcium alginate-tipped swab, wooden shaft swab, dry swabs, swab containing gel or charcoal
​Formalin-fixed and/or paraffin-embedded tissues
Useful For
Detection of Ureaplasma urealyticum and U parvum from urogenital, bone and joint, and lower respiratory sources.
Test Information
Ureaplasma urealyticum and U parvum have been associated with a number of clinically significant infections, although their clinical significance may not always be clear as they are part of the normal genital flora. U urealyticum and U parvum have been associated with urethritis and epididymitis. They may cause upper urinary tract infection and they have been associated with infected renal stones. U urealyticum and U parvum may be isolated from amniotic fluid of women with preterm labor, premature rupture of membranes, spontaneous term labor, or chorioamnionitis. They may also cause neonatal infections, including meningoencephalitis and pneumonia. In addition, U urealyticum and U parvum have been reported to cause unusual infections, such as prosthetic joint infection and infections in transplant recipients.
 
Culture of Ureaplasma species is laborious, requiring a high degree of technical skill and taking several days. PCR detection is sensitive, specific, and provides same-day results. In addition, PCR allows the differentiation of U urealyticum and U parvum, which is not easily accomplished with culture. PCR assay has replaced conventional culture for U urealyticum and U parvum due to its speed and equivalent performance to culture.
Reference Range Information
Performing Location Reference Range
​Mayo Medical Laboratories ​Negative
Interpretation
A positive PCR result for the presence of a specific sequence found within the Ureaplasma urealyticum and U parvum ureC gene indicates the presence of U urealyticum or U parvum DNA in the specimen.
 
A negative PCR result indicates the absence of detectable U urealyticum and U parvum DNA in the specimen, but does not rule-out infection as false-negative results may occur due to inhibition of PCR, sequence variability underlying the primers and probes, or the presence of U urealyticum or U parvum in quantities less than the limit of detection of the assay.
For more information visit:
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
​Mayo Medical Laboratories ​Monday through Friday ​3 days Real-Time Polymerase Chain Reaction (PCR) Using LightCycler and Fluorescent Resonance Energy Transfer (FRET)
Reference Lab
For billing questions, see Contacts
Outreach CPTs
CPT Modifier
(if needed)
Quantity Description Comments
​87798 ​2
For most current information refer to the Marshfield Laboratory online reference manual.