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25123 Connective Tissue Disease Panel

Connective Tissue Disease Panel
Test Code: CTDP
Synonyms/Keywords
Rheumatoid Arthritis, RA, RA-IgM, Lupus, SLE, CREST syndrome, Sjogren's syndrome, scleroderma, polymyositis, dermatomyositis​
Test Components
This panel tests for Rheumatoid Factor (RA-IgM), Cyclic Citrullinated Peptide (CCP), and Antinuclear antibodies (ANA).​
Useful For
For the screening and diagnosis of patients with symptoms of mixed connective tissue diseases such as:  systemic lupus erythematosus (SLE), systemic sclerosis, myositis, Sjogren's syndrome, and rheumatoid arthritis.  ​
Specimen Requirements
Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)
Pediatric Minimum Volume
(no repeat)
No​ Serum​ Red Top Tube (RTT) ​ Serum Separator Tube (SST)​ 1.5  mL​ 1.0 mL​ 1.0 mL​
Specimen Stability Information
Specimen Type Temperature Time
Serum​ ​ Refrigerate​ 2 days​
Frozen > 2 days​
Rejection Criteria
Gross hemolysis
Gross lipemia​
Heat inactivated samples​
Gross icterus
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
Marshfield​ Monday through Friday​ 2 days​

RA: Turbidimetric Method (Binding Site/Optilite)

ANA: Indirect Immunofluorescence

CCP:Multiplex Flow Immunoassay/Bio-Rad BioPlex 2200 ​

Reference Range Information
Performing Location Reference Range
Marshfield ​

RA: <=13 IU/mL

ANA: Negative

CCP: 0 - 2.9 IU/mL ​

Outreach CPTs
CPT Modifier
(if needed)
Quantity Description Comments
86200​ 1​ CCP​
86431​ ​1 RA​
86038 ​ ​1 ANA​
Synonyms/Keywords
Rheumatoid Arthritis, RA, RA-IgM, Lupus, SLE, CREST syndrome, Sjogren's syndrome, scleroderma, polymyositis, dermatomyositis​
Test Components
This panel tests for Rheumatoid Factor (RA-IgM), Cyclic Citrullinated Peptide (CCP), and Antinuclear antibodies (ANA).​
Ordering Applications
Ordering Application Description
​Centricity ​Connective Tissue Disease Pnl
​Cerner ​None
​COM ​Connective Tissue Disease Pnl
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)
Pediatric Minimum Volume
(no repeat)
No​ Serum​ Red Top Tube (RTT) ​ Serum Separator Tube (SST)​ 1.5  mL​ 1.0 mL​ 1.0 mL​
Specimen Stability Information
Specimen Type Temperature Time
Serum​ ​ Refrigerate​ 2 days​
Frozen > 2 days​
Rejection Criteria
Gross hemolysis
Gross lipemia​
Heat inactivated samples​
Gross icterus
Useful For
For the screening and diagnosis of patients with symptoms of mixed connective tissue diseases such as:  systemic lupus erythematosus (SLE), systemic sclerosis, myositis, Sjogren's syndrome, and rheumatoid arthritis.  ​
Test Components
This panel tests for Rheumatoid Factor (RA-IgM), Cyclic Citrullinated Peptide (CCP), and Antinuclear antibodies (ANA).​
Reference Range Information
Performing Location Reference Range
Marshfield ​

RA: <=13 IU/mL

ANA: Negative

CCP: 0 - 2.9 IU/mL ​

For more information visit:
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
Marshfield​ Monday through Friday​ 2 days​

RA: Turbidimetric Method (Binding Site/Optilite)

ANA: Indirect Immunofluorescence

CCP:Multiplex Flow Immunoassay/Bio-Rad BioPlex 2200 ​

For billing questions, see Contacts
Outreach CPTs
CPT Modifier
(if needed)
Quantity Description Comments
86200​ 1​ CCP​
86431​ ​1 RA​
86038 ​ ​1 ANA​
For most current information refer to the Marshfield Laboratory online reference manual.