Results obtained with this test should not be considered conclusive evidence of the presence or absence of GI bleeding or pathology. This test is designed for preliminary screening, and is not intended to replace other diagnostic procedures, such as colonscopy or sigmoidoscopy in combination with double contrast barium x-ray.
Certain medications such as aspirin and non-steroidal anti-inflammatory drugs may cause gastrointestinal irritaition and subsequent bleeding in some patients and cause positive resuls.
Because gastrointestinal lesions may bleed intermittently and blood in feces is not distributed uniformly, a negative tests result does not ensure absence of lesion.