Creatinine Clearance (Uncorr. for Ht/Wt)

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Test Code: CRCL

Overview
Ordering
Specimen
Performing
Clinical/Interpretive
Contacts
Coding

Synonyms/Keywords

CRCL, Creatinine Clearance

Test Components

Urine and Blood Creatinine

Specimen Requirements

Fasting Required	Specimen Type	Preferred Container/Tube	Acceptable Container/Tube	Specimen Volume	Specimen Minimum Volume (allows for 1 repeat)	Pediatric Minimum Volume (no repeat)
No	24 Hour Urine	24 Hour Urine jug without preservative	24 Hour Urine jug with 7 g sulfamic acid, 20 mL 6 N HCL, 25 mL 33% acetic acid, 10 g boric acid, or 5 g sodium carbonate	10 mL	0.5 mL
No	Plasma/Serum (*See Collection Instructions)	Lithium-heparin Plasma Separator Tube (PST)	Serum Separator Tube (SST), Lithium or Sodium-Heparinized Green Top Tube (GTT) or Red Top Tube (RTT)	1 mL	0.3 mL

Collection Processing Instructions

*If there is no other blood creatinine order on the same encounter within 24 hours of urine collection a blood order of .CREAT (Creatinine Level) will be reflexed when the urine order is completely activated and should be drawn when the patient returns the timed urine collection.

Note: Blood specimens are acceptable no earlier than 24 hours prior to the start of the urine collection or no later than 24 hours after the collection ends.

Urine

Indicate the collection time.
The total volume collected must be measured, recorded, and included with the test request.

See Urine Preservative Cross-Reference 24-Hour and Other Timed Urine for preservative information.

Specimen Stability Information

Specimen Type	Temperature	Time
Urine - No Preservative	Ambient	2 hours
Urine - No Preservative	Refrigerate	4 days
Urine - W/Preservative	Refrigerate	7 days
Plasma/Serum	Ambient	7 days
Plasma/Serum	Refrigerate	7 days

Rejection Criteria

If either the blood or urine specimen is not available, the test cannot be performed.

Performing Laboratory Information

Performing Location	Day(s) Test Performed	Analytical Time	Methodology/Instrumentation
Beaver Dam	Monday through Sunday	Less than 2 hours	Modified Jaffe Reaction/ Siemens Dimension
Marshfield	Monday through Sunday	Less than 2 hours	Modified Jaffe Kinetic Fixed Assay/ Beckman Coulter AU
Rice Lake	Monday through Sunday	Less than 2 hours	Modified Jaffe Reaction/ Siemens Dimension
Weston	Monday through Sunday	Less than 2 hours	Modified Jaffe Reaction/ Siemens Atellica

Reference Range Information

Performing Location	Reference Range
All Performing Sites	CLEARANCE, mL/min. 1.73m2 MALE 0 - 1 month: 40 - 65 2 mo - 19 yrs: 92 - 150 20 - 29 years: 85 - 143 30 - 39 years: 78 - 136 40 - 49 years: 72 - 130 50 - 64 years: 65 - 123 > 65 yrs: 58 - 116 FEMALE 0 - 1 month: 40 - 65 2 mo - 19 yrs: 86 - 140 20 - 29 years: 79 - 133 30 - 39 years: 73 - 126 40 - 49 years: 67 - 121 50 - 64 years: 60 - 114 > 65 yrs: 54 - 108

Outreach CPTs

CPT	Modifier (if needed)	Quantity	Description	Comments
82570			Creatinine, other source
82565			Creatinine, blood	If needed

Synonyms/Keywords

CRCL, Creatinine Clearance

Test Components

Urine and Blood Creatinine

Ordering Applications

Ordering Application	Description
Cerner	Creatinine Clearance (Uncorr. for Ht/Wt) CRCL
4media	Creatinine Clearance (Uncorr. for Ht/Wt)

If the ordering application you are looking for is not listed, contact your local laboratory for assistance.

Specimen Requirements

Fasting Required	Specimen Type	Preferred Container/Tube	Acceptable Container/Tube	Specimen Volume	Specimen Minimum Volume (allows for 1 repeat)	Pediatric Minimum Volume (no repeat)
No	24 Hour Urine	24 Hour Urine jug without preservative	24 Hour Urine jug with 7 g sulfamic acid, 20 mL 6 N HCL, 25 mL 33% acetic acid, 10 g boric acid, or 5 g sodium carbonate	10 mL	0.5 mL
No	Plasma/Serum (*See Collection Instructions)	Lithium-heparin Plasma Separator Tube (PST)	Serum Separator Tube (SST), Lithium or Sodium-Heparinized Green Top Tube (GTT) or Red Top Tube (RTT)	1 mL	0.3 mL

Collection Processing

Note: Blood specimens are acceptable no earlier than 24 hours prior to the start of the urine collection or no later than 24 hours after the collection ends.

Urine

Indicate the collection time.
The total volume collected must be measured, recorded, and included with the test request.

See Urine Preservative Cross-Reference 24-Hour and Other Timed Urine for preservative information.

Specimen Stability Information

Specimen Type	Temperature	Time
Urine - No Preservative	Ambient	2 hours
Urine - No Preservative	Refrigerate	4 days
Urine - W/Preservative	Refrigerate	7 days
Plasma/Serum	Ambient	7 days
Plasma/Serum	Refrigerate	7 days

Rejection Criteria

If either the blood or urine specimen is not available, the test cannot be performed.

Test Components

Urine and Blood Creatinine

Reference Range Information

Performing Location	Reference Range
All Performing Sites	CLEARANCE, mL/min. 1.73m2 MALE 0 - 1 month: 40 - 65 2 mo - 19 yrs: 92 - 150 20 - 29 years: 85 - 143 30 - 39 years: 78 - 136 40 - 49 years: 72 - 130 50 - 64 years: 65 - 123 > 65 yrs: 58 - 116 FEMALE 0 - 1 month: 40 - 65 2 mo - 19 yrs: 86 - 140 20 - 29 years: 79 - 133 30 - 39 years: 73 - 126 40 - 49 years: 67 - 121 50 - 64 years: 60 - 114 > 65 yrs: 54 - 108

For more information visit:

http://labtestsonline.org

Performing Laboratory Information

Performing Location	Day(s) Test Performed	Analytical Time	Methodology/Instrumentation
Beaver Dam	Monday through Sunday	Less than 2 hours	Modified Jaffe Reaction/ Siemens Dimension
Marshfield	Monday through Sunday	Less than 2 hours	Modified Jaffe Kinetic Fixed Assay/ Beckman Coulter AU
Rice Lake	Monday through Sunday	Less than 2 hours	Modified Jaffe Reaction/ Siemens Dimension
Weston	Monday through Sunday	Less than 2 hours	Modified Jaffe Reaction/ Siemens Atellica

For billing questions, see Contacts

Outreach CPTs

CPT	Modifier (if needed)	Quantity	Description	Comments
82570			Creatinine, other source
82565			Creatinine, blood	If needed

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For most current information refer to the Marshfield Laboratory online reference manual.

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26546 Creatinine Clearance (Uncorr. for Ht/Wt)