Cadmium (Cd), Cd (Cadmium)
Detecting occupational exposure to cadmium, a toxic heavy metal in random urine specimens.
High concentrations of gadolinium and iodine are known to interfere with most metals tests. If either gadolinium- or iodine-containing contrast media has been administered, a specimen should not be collected for 96 hours.
Collection of urine specimens through a catheter frequently results in elevated values, because rubber contains trace amounts of cadmium that are extracted as urine passes through the catheter.
CDOU: Inductively Coupled Plasma-Mass Spectrometry (ICP-MS)
CRETR: Enzymatic Colorimetric Assay
Urine cadmium levels primarily reflect total body burden of cadmium. Cadmium excretion above 3.0 mcg/g creatinine indicates significant exposure to cadmium.
For occupational testing, the Occupational Safety and Health Administration (OSHA) cadmium standard is below 3.0 mcg/g creatine and the biological exposure index is 5 mcg/g creatinine.