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Red Cell Genotyping Panel (3530)
Test Code: RBCGNSO
Synonyms/Keywords
Red Cell Genotyping Panel (44 antigens reported**):
M, N, S, s, U, (including Uvar); C, c, E, e (including partial C, partial c, partial e),
V (Rh10), hrS (Rh19), VS (Rh20), hrB (Rh31); K, k, Kpa, Kpb, Jsa, Jsb; Fya, Fyb;
Jka, Jkb; Doa, Dob; Hy, Joa; Lua, Lub; Dia, Dib; Yta, Ytb; Coa, Cob; Cra; Vel
** The following Rh antigens are reported as necessary: Crawford (RH43), JAL (RH48), STEM (RH49), CEST (RH57), CELO (RH58), CEAG (RH59), CEVF (RH61).
Useful For

When phenotyping is not possible due to recent transfusion or a positive DAT.

To help resolve the weak expression of blood group antigens, for example when two or more serological reagents give conflicting results.

When a partial or variant antigen is present leading to conflicting serological antibody investigations.

To provide antigen-negative and crossmatch-compatible blood to help prevent red cell alloimmunization.

To meet the requirements for ordering rare blood from the ARDP*. * The following alleles are provided on patients for ARDP requests: ce(48C), ce(733G), ceS, ceMO, ceEK, ceBI, ceAR, ceAG, ceJAL, ceCF, and ceTI.

Specimen Requirements
Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)
Pediatric Minimum Volume
(no repeat)
​No ​Whole Blood ​EDTA Lavender Top Tube (LTT) ​EDTA Pink Top Tube (PTT) ​5 mL ​3 mL
Collection Processing Instructions
​Collect blood in original tube, invert 3-5 times, store and ship at room termperature.
Specimen Stability Information
Specimen Type Temperature Time
​Whole Blood ​ ​Room Temperature ​7 days
​Refrigerate ​14 days
Interference
​Mutations outside of the targeted region will not be detected.  Novel mutations leading to altered or partial antigen expression and null phenotypes may not be detected by this testing method.  Results from stem cell transplant patients may not match genotype obtained fro other tissues.
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
​Versiti/​Blood Center of Wisconsin ​Monday through Friday ​3-6 days ​PCR and Hybridization Probes
Reference Range Information
Performing Location Reference Range
Outreach CPTs
CPT Modifier
(if needed)
Quantity Description Comments
Synonyms/Keywords
Red Cell Genotyping Panel (44 antigens reported**):
M, N, S, s, U, (including Uvar); C, c, E, e (including partial C, partial c, partial e),
V (Rh10), hrS (Rh19), VS (Rh20), hrB (Rh31); K, k, Kpa, Kpb, Jsa, Jsb; Fya, Fyb;
Jka, Jkb; Doa, Dob; Hy, Joa; Lua, Lub; Dia, Dib; Yta, Ytb; Coa, Cob; Cra; Vel
** The following Rh antigens are reported as necessary: Crawford (RH43), JAL (RH48), STEM (RH49), CEST (RH57), CELO (RH58), CEAG (RH59), CEVF (RH61).
Ordering Applications
Ordering Application Description
​Clinical Order Manager ​Red Cell Genotyping Panel (3530)
​Cerner ​Red Cell Genotyping Panel (3530)
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)
Pediatric Minimum Volume
(no repeat)
​No ​Whole Blood ​EDTA Lavender Top Tube (LTT) ​EDTA Pink Top Tube (PTT) ​5 mL ​3 mL
Collection Processing Instructions
​Collect blood in original tube, invert 3-5 times, store and ship at room termperature.
Specimen Stability Information
Specimen Type Temperature Time
​Whole Blood ​ ​Room Temperature ​7 days
​Refrigerate ​14 days
Interference
​Mutations outside of the targeted region will not be detected.  Novel mutations leading to altered or partial antigen expression and null phenotypes may not be detected by this testing method.  Results from stem cell transplant patients may not match genotype obtained fro other tissues.
Useful For

When phenotyping is not possible due to recent transfusion or a positive DAT.

To help resolve the weak expression of blood group antigens, for example when two or more serological reagents give conflicting results.

When a partial or variant antigen is present leading to conflicting serological antibody investigations.

To provide antigen-negative and crossmatch-compatible blood to help prevent red cell alloimmunization.

To meet the requirements for ordering rare blood from the ARDP*. * The following alleles are provided on patients for ARDP requests: ce(48C), ce(733G), ceS, ceMO, ceEK, ceBI, ceAR, ceAG, ceJAL, ceCF, and ceTI.

Reference Range Information
Performing Location Reference Range
For more information visit:
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
​Versiti/​Blood Center of Wisconsin ​Monday through Friday ​3-6 days ​PCR and Hybridization Probes
For billing questions, see Contacts
Outreach CPTs
CPT Modifier
(if needed)
Quantity Description Comments
For most current information refer to the Marshfield Laboratory online reference manual.