Disinfectants (such as Betadine) that contain iodine should not be used during venipuncture.
High concentrations of gadolinium and iodine are known to interfere with most metals tests. If either gadolinium or iodine containing contrast media has been administered, a specimen should not be collected for 96 hours.
Iodine is an essential element that is required for thyroid hormone production. The measurement of iodine serves as an index of adequate dietary iodine intake and iodine overload, particularly from iodine-containing drugs such as amiodarone
Values between 80 ng/mL and 250 ng/mL have been reported to indicate hyperthyroidism.
Values >250 ng/mL may indicate iodine overload.