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26040 Iodine, Serum (IOD)

Iodine, Serum (IOD)
Test Code: IODSO
Useful For
Determination of iodine overload using serum specimens
Monitoring iodine levels in individuals taking iodine-containing drugs
Specimen Requirements
Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)
Pediatric Minimum Volume
(no repeat)
​No ​Serum Plain, royal blue-top top Vacutainer plastic trace element blood collection tube​ ​1.0 mL ​0.3 mL
Collection Processing Instructions

Disinfectants (such as Betadine) that contain iodine should not be used during venipuncture.

High concentrations of gadolinium and iodine are known to interfere with most metals tests. If either gadolinium or iodine containing contrast media has been administered, a specimen should not be collected for 96 hours.

 
Allow specimen to clot for 30 minutes; then centrifuge the specimen to separate serum from the cellular fraction. Remove the stopper. Carefully pour specimen into Mayo metal-free, polypropylene vial, avoiding transfer of the cellular components of blood. Do not insert a pipet into the serum to accomplish transfer, and do not ream the specimen with a wooden stick to assist with serum transfer.
Specimen Stability Information
Specimen Type Temperature Time
​Serum ​ ​ ​Refrigerate (preferred) ​21 days
​Ambient ​21 days
​Frozen ​21 days
Interference
There are no known analytical interferences with this procedure.
Administration of iodine-containing contrast media will yield elevated results.
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
​Mayo Clinic Laboratories ​Monday, Wednesday, Friday ​1-3 days ​Inductively Coupled Plasma-Mass Spectrometer (ICP-MS)
Reference Lab
Test Information

​Iodine is an essential element that is required for thyroid hormone production. The measurement of iodine serves as an index of adequate dietary iodine intake and iodine overload, particularly from iodine-containing drugs such as amiodarone

Reference Range Information
Performing Location Reference Range
​Mayo Clinic Laboratories ​40-92 ng/mL
Interpretation

Values between 80 ng/mL and 250 ng/mL have been reported to indicate hyperthyroidism.

Values >250 ng/mL may indicate iodine overload.

Outreach CPTs
CPT Modifier
(if needed)
Quantity Description Comments
​83789 ​1
Ordering Applications
Ordering Application Description
​Centricity ​Iodine, Serum (IOD)
​Cerner ​Iodine, Serum (IOD)
​COM ​Iodine, Serum (IOD)
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)
Pediatric Minimum Volume
(no repeat)
​No ​Serum Plain, royal blue-top top Vacutainer plastic trace element blood collection tube​ ​1.0 mL ​0.3 mL
Collection Processing

Disinfectants (such as Betadine) that contain iodine should not be used during venipuncture.

High concentrations of gadolinium and iodine are known to interfere with most metals tests. If either gadolinium or iodine containing contrast media has been administered, a specimen should not be collected for 96 hours.

 
Allow specimen to clot for 30 minutes; then centrifuge the specimen to separate serum from the cellular fraction. Remove the stopper. Carefully pour specimen into Mayo metal-free, polypropylene vial, avoiding transfer of the cellular components of blood. Do not insert a pipet into the serum to accomplish transfer, and do not ream the specimen with a wooden stick to assist with serum transfer.
Specimen Stability Information
Specimen Type Temperature Time
​Serum ​ ​ ​Refrigerate (preferred) ​21 days
​Ambient ​21 days
​Frozen ​21 days
Interference
There are no known analytical interferences with this procedure.
Administration of iodine-containing contrast media will yield elevated results.
Useful For
Determination of iodine overload using serum specimens
Monitoring iodine levels in individuals taking iodine-containing drugs
Reference Range Information
Performing Location Reference Range
​Mayo Clinic Laboratories ​40-92 ng/mL
Interpretation

Values between 80 ng/mL and 250 ng/mL have been reported to indicate hyperthyroidism.

Values >250 ng/mL may indicate iodine overload.

For more information visit:
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
​Mayo Clinic Laboratories ​Monday, Wednesday, Friday ​1-3 days ​Inductively Coupled Plasma-Mass Spectrometer (ICP-MS)
Reference Lab
For billing questions, see Contacts
Outreach CPTs
CPT Modifier
(if needed)
Quantity Description Comments
​83789 ​1
For most current information refer to the Marshfield Laboratory online reference manual.