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25544 Histoplasma Antigen, Quantitative, Serum/Plasma (310)

Histoplasma Antigen, Quantitative, Serum/Plasma (310)
Test Code: HTAGSSO
Synonyms/Keywords

​​Histoplasma Capsulatum QNT AG

Useful For

Aids the diagnosis of histoplasmosis

Monitor the response to therapy and determine when treatment can be stopped

Monitor Histoplasma antigen levels to help determine relapses of disease

Specimen Requirements
Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Minimum Volume
(allows for 1 repeat)
​Serum ​Red Top Tube (RTT) ​Serum Separator Tube (SST) ​0.8 mL
​Plasma ​EDTA Lavender Top Tube (LTT)

​Sodium-heparin OR Lithium-heparin Green Top Tube (GTT)

OR

Sodium citrate tube (BTT)

 ​0.8 mL
Collection Processing Instructions

Serum:
Collect serum specimens in serum separator or red top tube.
Allow blood to clot for 30 minutes, then centrifuge.
Pipette serum into a plastic screw cap vial.

Plasma:
Collect plasma specimens in an EDTA, heparin or sodium citrate tube.
Centrifuge for 15 minutes and pipette plasma into a plastic screw cap vial. 

​Ship next day service for Monday - Friday delivery.

Specimen Stability Information
Specimen Type Temperature Time
​Serum ​ ​ ​Ambient ​14 days
​Refrigerated ​14 days
​Frozen ​Indefinitely
Rejection Criteria

If specimen is too viscous to pipette

Tissue, Sputum, Bronchial Brushings, Stool, FNA, Biopsy, Tracheal or Bone Marrow Aspirate

Stored in Transport Media, Fixative or Isolator Tubes

Interference

​The result is not intended to be used as the sole means for the clinical diagnosis or patient management decisions.

Cross-reactions are seen with blastomycosis, paracoccidioidomycosis, penicilliosis, less frequently in coccidioidomycosis, rarely in aspergillosis and possibly sporotrichosis.

Sputolysin, sodium hydroxide and potassium hydroxide treatment degrade the analyte detected in the assay.

Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
​MiraVista Diagnostics ​Monday through Friday 1 day

​Quantitative Sandwich Enzyme Immunoassay (EIA)

Serum is pre-treated to improve sensitivity.  This adds 1 day to TAT.

Reference Lab
Miravista Diagnostics
Test Information

Positive samples may require confirmation which could extend TAT. 

Reference Range Information

None Detected

Interpretation

Reference Interval:  None Detected

Reportable Range:  Positive:  0.20 ng/mL to 20.00 ng/mL
  Positive results above 20.00 ng/mL are reported as "Above the Limit of Quantification"

Results greater than 20.00 ng/mL fall outside the linear range of the assay. These results are positive, but not accurately quantifiable.

Cross-reactions occur with blastomyces spp., Coccidioides spp., and Paracoccidioides brasiliensis
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
​87385 ​ ​1
 ​ ​
Synonyms/Keywords

​​Histoplasma Capsulatum QNT AG

Ordering Applications
Ordering Application Description
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Minimum Volume
(allows for 1 repeat)
​Serum ​Red Top Tube (RTT) ​Serum Separator Tube (SST) ​0.8 mL
​Plasma ​EDTA Lavender Top Tube (LTT)

​Sodium-heparin OR Lithium-heparin Green Top Tube (GTT)

OR

Sodium citrate tube (BTT)

 ​0.8 mL
Collection Processing

Serum:
Collect serum specimens in serum separator or red top tube.
Allow blood to clot for 30 minutes, then centrifuge.
Pipette serum into a plastic screw cap vial.

Plasma:
Collect plasma specimens in an EDTA, heparin or sodium citrate tube.
Centrifuge for 15 minutes and pipette plasma into a plastic screw cap vial. 

​Ship next day service for Monday - Friday delivery.

Specimen Stability Information
Specimen Type Temperature Time
​Serum ​ ​ ​Ambient ​14 days
​Refrigerated ​14 days
​Frozen ​Indefinitely
Rejection Criteria

If specimen is too viscous to pipette

Tissue, Sputum, Bronchial Brushings, Stool, FNA, Biopsy, Tracheal or Bone Marrow Aspirate

Stored in Transport Media, Fixative or Isolator Tubes

Interference

​The result is not intended to be used as the sole means for the clinical diagnosis or patient management decisions.

Cross-reactions are seen with blastomycosis, paracoccidioidomycosis, penicilliosis, less frequently in coccidioidomycosis, rarely in aspergillosis and possibly sporotrichosis.

Sputolysin, sodium hydroxide and potassium hydroxide treatment degrade the analyte detected in the assay.

Useful For

Aids the diagnosis of histoplasmosis

Monitor the response to therapy and determine when treatment can be stopped

Monitor Histoplasma antigen levels to help determine relapses of disease

Reference Range Information

None Detected

Interpretation

Reference Interval:  None Detected

Reportable Range:  Positive:  0.20 ng/mL to 20.00 ng/mL
  Positive results above 20.00 ng/mL are reported as "Above the Limit of Quantification"

Results greater than 20.00 ng/mL fall outside the linear range of the assay. These results are positive, but not accurately quantifiable.

Cross-reactions occur with blastomyces spp., Coccidioides spp., and Paracoccidioides brasiliensis
For more information visit:
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
​MiraVista Diagnostics ​Monday through Friday 1 day

​Quantitative Sandwich Enzyme Immunoassay (EIA)

Serum is pre-treated to improve sensitivity.  This adds 1 day to TAT.

Reference Lab
Miravista Diagnostics
For billing questions, see Contacts
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
​87385 ​ ​1
 ​ ​
For most current information refer to the Marshfield Laboratory online reference manual.