Detect and quantitate PML-RARA fusion transcripts in patients with acute promyelocytic leukemia.
Monitor minimal residual disease and assess the risk of disease relapse.
This assay qualifies as COG approved for the AAML0631 study.
Call Cytogenetics at 16388 with cases associated to the AAML0631 study.
Specimens must be received with 48 hours of collection due to lability of RNA.
Whole Blood and Bone Marrow: CRITICAL REFRIGERATED. Separate specimens must be submitted when multiple tests are ordered.
For Extracted RNA: CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.
Serum, plasma, CSF, extracted DNA, RNA extracted by a non-CLIA lab, bone core, or FFPE tissue
Specimens collected in anticoagulants other than EDTA
Severely hemolyzed or clotted specimens
RNA Isolation: Sunday- Saturday
Assay: Sunday, Tuesday, Thursday