You may be trying to access this site from a secured browser on the server. Please enable scripts and reload this page.
Turn on more accessible mode
Turn off more accessible mode
Skip Ribbon Commands
Skip to main content
Turn off Animations
Turn on Animations
Sign In
This page location is:
Lab Test Reference Manual
Human Reference Manual
Pages
25378
Lab Test Reference Manual
Human Reference Manual
Currently selected
25378
Carbohydrate Antigen 19-9, Body Fluid
Marshfield Lab Public WebSite
Marshfield Clinic Public WebSite
It looks like your browser does not have JavaScript enabled. Please turn on JavaScript and try again.
Search
Test Code
Laboratory Section
All
Test Category
All
Browse By Test Name
#
A
B
C
D
E
F
G
H
I
J
K
L
M
N
O
P
Q
R
S
T
U
V
W
X
Y
Z
Additional Information
Libraries
Newsletter Document Library
Regional Menus Pages
Lists
Lab Clinical Practice Guidelines
Antimicrobial Susceptibility Panels
Toxicology Information
Urine Preservatives
Requisition Forms and Instructions
Testing
Newsletter Links
Newsletters 2014
Newsletters 2015
Newsletters 2016
Newsletters 2017
Newsletters 2018
Cumulative Antibiogram Reports
testz
Human Test Code IDs
Recent
Newsletters 2024
Newsletters 2023
Newsletters 2022
Antibiogram-PDFs
Newsletters 2021
Site Contents
Carbohydrate Antigen 19-9, Body Fluid
Test Code: CA19-9O
Overview
Ordering
Specimen
Performing
Clinical/Interpretive
Contacts
Coding
Useful For
Useful For
An adjunct marker in the assessment of pancreatic cysts when used in conjunction with CEA, amylase, imaging studies and cytology.
An adjuvant to cytology and imaging studies to differentiate between nonmalignant and malignant causes of pleural effusions & peritoneal fluid.
Specimen Requirements
Specimen Requirements
Specimen Type
Preferred Container/Tube
Acceptable Container/Tube
Specimen Volume
Specimen Minimum Volume
(allows for 1 repeat)
Pediatric Minimum Volume
(no repeat)
Pancreatic Cyst Fluid / Body Fluid
Body Fluid container
Plastic vial
300 uL
100 uL
N/A
Collection Processing Instructions
Collection Processing
Do not collect the specimen with preservatives or anticoagulants. Specimens should be centrifuged to remove cells or clots if present.
Specimen Stability Information
Specimen Stability Information
Specimen Type
Temperature
Time
Pancreatic Cyst Fluid / Body Fluid
Ambient
N/A
Refrigerated
7 days
Frozen at -20 deg Celsius
30 days
Frozen at -70 deg Celsius
> 30 days
Rejection Criteria
Rejection Criteria
Blood or Urine
Interference
Interference
The possibility exists for interference by heterophile antibodies & HAMA in the patient sample regularly exposed to animals or has received immunotherapy or diagnostic procedures utilizing immunoglobulins or immunoglobulin fragments.
Performing Laboratory Information
Performing Laboratory Information
Performing Location
Day(s) Test Performed
Analytical Time
Methodology/Instrumentation
Marshfield
Monday through Friday
Less than 2 hours
Two-step Sandwich Immunoassay using Direct Chemiluminometric Technology/Siemens Centaur
Reference Range Information
Reference Range Information
Performing Location
Reference Range
Marshfield
Reference cut-off limits for CEA for pancreatic cyst fluid and other body fluids have not been established and verified.
The test results should not be the sole basis of diagnosis and always be correlated with imaging and cytology.
Interpretation
Interpretations
Diagnosis of a pancreatic cyst is often difficult and requires correlation of imaging studies, cytology studies and tumor marker results on cyst aspirates. High concentrations of Carbohydrate antigen 19-9 (CA 19-9) in pancreatic cyst fluid may be helpful in distinguishing between benign and malignant cysts.
Based on evidence available and recommendations by the American College of Gastroenterology (ACG) practice guidelines for the Diagnosis and Management of Neoplastic Pancreatic Cysts (Am. J. Gastroenterol. 2007; 102: 2339-2349), a pancreatic cyst fluid CA 19-9 < 37 U/ml has high specificity to excludes mucinous cyst. A low (<5 U/ml) or negative result may be uninformative or misleading as some individuals do not produce CA 19-9 antigens. Serum CA 19-9 should be measured to verify if a patient is a CA 19-9 secretor or not.
This test should be performed in conjunction with CEA & Amylase and should not be ordered for pancreatic fluid of non-cyst origin.
Outreach CPTs
Outreach CPT Codes
CPT
Modifier
(if needed)
Quantity
Description
Comments
86301
Ordering Applications
Ordering Applications
Ordering Application
Description
COM
CA 19-9, Body Fluid
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
Specimen Requirements
Specimen Type
Preferred Container/Tube
Acceptable Container/Tube
Specimen Volume
Specimen Minimum Volume
(allows for 1 repeat)
Pediatric Minimum Volume
(no repeat)
Pancreatic Cyst Fluid / Body Fluid
Body Fluid container
Plastic vial
300 uL
100 uL
N/A
Collection Processing
Collection Processing
Do not collect the specimen with preservatives or anticoagulants. Specimens should be centrifuged to remove cells or clots if present.
Specimen Stability Information
Specimen Stability Information
Specimen Type
Temperature
Time
Pancreatic Cyst Fluid / Body Fluid
Ambient
N/A
Refrigerated
7 days
Frozen at -20 deg Celsius
30 days
Frozen at -70 deg Celsius
> 30 days
Rejection Criteria
Rejection Criteria
Blood or Urine
Interference
Interference
The possibility exists for interference by heterophile antibodies & HAMA in the patient sample regularly exposed to animals or has received immunotherapy or diagnostic procedures utilizing immunoglobulins or immunoglobulin fragments.
Useful For
Useful For
An adjunct marker in the assessment of pancreatic cysts when used in conjunction with CEA, amylase, imaging studies and cytology.
An adjuvant to cytology and imaging studies to differentiate between nonmalignant and malignant causes of pleural effusions & peritoneal fluid.
Reference Range Information
Reference Range Information
Performing Location
Reference Range
Marshfield
Reference cut-off limits for CEA for pancreatic cyst fluid and other body fluids have not been established and verified.
The test results should not be the sole basis of diagnosis and always be correlated with imaging and cytology.
Interpretation
Interpretations
Diagnosis of a pancreatic cyst is often difficult and requires correlation of imaging studies, cytology studies and tumor marker results on cyst aspirates. High concentrations of Carbohydrate antigen 19-9 (CA 19-9) in pancreatic cyst fluid may be helpful in distinguishing between benign and malignant cysts.
Based on evidence available and recommendations by the American College of Gastroenterology (ACG) practice guidelines for the Diagnosis and Management of Neoplastic Pancreatic Cysts (Am. J. Gastroenterol. 2007; 102: 2339-2349), a pancreatic cyst fluid CA 19-9 < 37 U/ml has high specificity to excludes mucinous cyst. A low (<5 U/ml) or negative result may be uninformative or misleading as some individuals do not produce CA 19-9 antigens. Serum CA 19-9 should be measured to verify if a patient is a CA 19-9 secretor or not.
This test should be performed in conjunction with CEA & Amylase and should not be ordered for pancreatic fluid of non-cyst origin.
For more information visit:
http://labtestsonline.org
Performing Laboratory Information
Performing Laboratory Information
Performing Location
Day(s) Test Performed
Analytical Time
Methodology/Instrumentation
Marshfield
Monday through Friday
Less than 2 hours
Two-step Sandwich Immunoassay using Direct Chemiluminometric Technology/Siemens Centaur
For billing questions, see Contacts
Outreach CPTs
Outreach CPT Codes
CPT
Modifier
(if needed)
Quantity
Description
Comments
86301
Return To Top
For most current information refer to the Marshfield Laboratory online reference manual.