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25244 Herpes Simplex and Varicella Zoster NAT Panel

Herpes Simplex and Varicella Zoster NAT Panel
Test Code: HSVZVP
Synonyms/Keywords
​​​HSV and VZV by PCR, Derm panel
Test Components
​HS12PCR, VZVPCR
Useful For
​Useful for detection and differentiation of VZV, HSV I and II DNA in CSF and vesicular fluid and cellular material from base of lesion (skin, mucosal, urogenital). This test should not be used to screen asymptomatic patients. In suspected cases of congenital herpes, order MISC for VHSV culture at Mayo Laboratories.
Specimen Requirements
Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
​No
​CSF
​Sterile, leak-proof vial
​

​1.0 mL
​0.5 mL
​0.2 mL
​No
 ​Swab - skin lesions ​Universal Transport Media (UTM)
 BD UVT, Remel M4, Remel M4RT, Remel M5, Remel M6
 1 swab

Specimen Stability Information
Specimen Type Temperature Time
​CSF
​

​Refrigerate
​7 days
​Frozen
​30 days
​Swab
 ​Refrigerate ​7 days
Rejection Criteria

​Wood-Shafted, Cotton, or Calcium Alginate Swabs
​Urine and Body Fluids (With the Exception of CSF)
​Solid Tissue Samples



Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
​Molecular Pathology ​Lesions: Monday through Friday
CSF: Monday through Sunday
6-8 hours*
 Real time PCR​
​ ​ *Testing performed once/day.​
​Sample must be re​ceived in the lab by 0400 to be tested same day.​ ​ ​
Test Information

HSVZVPCR is a real-time polymerase chain reaction (PCR) based qualitative in vitro diagnostic test for the direct amplification and detection of HSV-1, HSV-2 and VZV DNA from unprocessed cutaneous and mucocutaneous lesion swab specimens and CSF.​

Negative results do not preclude VZV, HSV-1 or HSV-2 infection and should not be used as the sole basis for treatment or other patient management decisions.

Reference Range Information
Interpretive report
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
​87529 ​ 2​
 ​HSV ​
​87798 ​ ​1 ​VZV ​
Synonyms/Keywords
​​​HSV and VZV by PCR, Derm panel
Test Components
​HS12PCR, VZVPCR
Ordering Applications
Ordering Application Description
​Centricity ​None
​Cerner ​Herpes Simplex and Varicella Zoster NAT Panel
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
​No
​CSF
​Sterile, leak-proof vial
​

​1.0 mL
​0.5 mL
​0.2 mL
​No
 ​Swab - skin lesions ​Universal Transport Media (UTM)
 BD UVT, Remel M4, Remel M4RT, Remel M5, Remel M6
 1 swab

Specimen Stability Information
Specimen Type Temperature Time
​CSF
​

​Refrigerate
​7 days
​Frozen
​30 days
​Swab
 ​Refrigerate ​7 days
Rejection Criteria

​Wood-Shafted, Cotton, or Calcium Alginate Swabs
​Urine and Body Fluids (With the Exception of CSF)
​Solid Tissue Samples



Useful For
​Useful for detection and differentiation of VZV, HSV I and II DNA in CSF and vesicular fluid and cellular material from base of lesion (skin, mucosal, urogenital). This test should not be used to screen asymptomatic patients. In suspected cases of congenital herpes, order MISC for VHSV culture at Mayo Laboratories.
Test Components
​HS12PCR, VZVPCR
Reference Range Information
Interpretive report
For more information visit:
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
​Molecular Pathology ​Lesions: Monday through Friday
CSF: Monday through Sunday
6-8 hours*
 Real time PCR​
​ ​ *Testing performed once/day.​
​Sample must be re​ceived in the lab by 0400 to be tested same day.​ ​ ​
For billing questions, see Contacts
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
​87529 ​ 2​
 ​HSV ​
​87798 ​ ​1 ​VZV ​
For most current information refer to the Marshfield Laboratory online reference manual.