HLA-matched platelets are indicated in patients who have become refractory to platelet transfusions due to HLA alloimmunization. Refer to HLA-Matched Platelets Requisition and Administration Procedure (DCS document).
Patient must have HLA typing (HLATX), and HLA Antibody Detection and Identification (HLAIDSO) completed before HLA-matched platelets can be ordered and available for transfusion. If HLA testing is required, turn around time for determination and availability of platelets is approximately 7-10 days. If HLA testing previously completed, turn around time for platelets is 2-3 days.
Refer to Versiti Lab Test Menu for specimen requirements for HLA-AB Low Resolution (2303) and HLA Antibody Identificaion Class I High Resolution (2226)
"Request for HLA Matched Platelets" PowerPlan must be completed for an initial request and any subsequent request more than 1 month from initial request for HLA-matched platelets. All questions within the power plan MUST be answered. If there are any questions after completing power plan, contact Lab/Transfusion Service. If Lab/Transfusion Service has questions about request for HLA-matched platelets, provider may be contacted.
When notified that HLA-matched platelet is available for transfusion, provider MUST place an order for transfusion when indicated. Use the routine Blood Product Transfusion Power plan. Provider should indicate under "Special Requirements-HLA Matched."
The recipient must have HLA typing (HLATX 2303) and HLA Antibody Detection and Identification (HLAIDSO 2226) prior to the availability of HLA-matched platelets.
Recipient must have blood type on file in Transfusion Service. Transfusion Service will communicate with the provider when HLA-matched platelets are available for transfusion. A order must be placed for each transfusion request.