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23466 Diphtheria Tetanus Antibody Panel (DTABS)

Diphtheria Tetanus Antibody Panel (DTABS)
Test Code: DIPTESO
Synonyms/Keywords
Anti-tetanus toxoid, C. tetani, Clostridium tetani, Corynebacterium diphtheriae Antitoxin, Diphtheria Antitoxoid, Tetanus Immune Response, Tetanus toxoid antibodies, Tetanus/Diphtheria Antibody Panel
Test Components
​Diphtheria Toxoid IgG Antibody
Tetanus Toxoid IgG Antibody
Useful For

Assessment of an antibody response to tetanus and diphtheria toxoid vaccines, which should be performed at least 3 weeks after immunization

Aiding in the evaluation of immunodeficiency

This test should not be used to diagnose tetanus infection 

Specimen Requirements
Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)
Pediatric Minimum Volume
(no repeat)
Serum​ ​Serum Separator Tube (SST) ​Red Top Tube (RTT) ​1 mL ​0.8 mL
Specimen Stability Information
Specimen Type Temperature Time
​Serum ​ ​Refrigerated (preferred) ​30 days
​Frozen ​30 days
Rejection Criteria
Gross Hemolysis
Gross ​Lipemia
​Gross Icterus
​Heat Inactivated Specimens
Performing Laboratory Information
Performing Location Day(s) Test Performed Report Available Methodology/Instrumentation
​Mayo Clinic Laboratories Monday through Friday​ ​1 to 4 days
Enzyme-Linked Immunosorbent Assay (ELISA)
Reference Lab
Test Information

This test should be regarded as 'Research Use Only'. This test has not been cleared or approved by the U.S. Food and Drug Administration. It may not be covered by insurance and providers need to inform all patients of this prior to ordering. 

For Medicare patients, an Advanced Beneficiary notice (ABN) is required; for Medicaid patients, a Noncovered Services Waiver is required, and for commercial payers, prior authorization should be obtained.  

Reference Range Information

DIPHTHERIA TOXOID IgG ANTIBODY

Vaccinated: Positive (> or =0.01 IU/mL)

Unvaccinated: Negative (<0.01 IU/mL)

Reference values apply to all ages.

 

TETANUS TOXOID IgG ANTIBODY

Vaccinated: Positive (> or =0.01 IU/mL)

Unvaccinated: Negative (<0.01 IU/mL)

Reference values apply to all ages.

Interpretation

Diphtheria:

Results of 0.01 IU/mL or more suggest a vaccine response.

A diphtheria toxoid booster should be considered for patients with antidiphtheria toxoid IgG values between 0.01 and less than 0.1 IU/mL

Tetanus:

Results of 0.01 IU/mL or more suggest a vaccine response.

A tetanus toxoid booster should strongly be considered for patients with antitetanus toxoid IgG values between 0.01 and 0.5 IU/mL.

Some cases of tetanus, usually mild, have occasionally been observed in patients who have a measurable serum level of 0.01 to 1.0 IU/mL.

Outreach CPTs
CPT Modifier
(if needed)
Quantity Description Comments
​86317 ​2
Classification

This test should be regarded as 'Research Use Only'. This test has not been cleared or approved by the U.S. Food and Drug Administration. It may not be covered by insurance and providers need to inform all patients of this prior to ordering. 

For Medicare patients, an Advanced Beneficiary notice (ABN) is required; for Medicaid patients, a Noncovered Services Waiver is required, and for commercial payers, prior authorization should be obtained.  

Synonyms/Keywords
Anti-tetanus toxoid, C. tetani, Clostridium tetani, Corynebacterium diphtheriae Antitoxin, Diphtheria Antitoxoid, Tetanus Immune Response, Tetanus toxoid antibodies, Tetanus/Diphtheria Antibody Panel
Test Components
​Diphtheria Toxoid IgG Antibody
Tetanus Toxoid IgG Antibody
Ordering Applications
Ordering Application Description
​Centricity ​Diphtheria Tetanus Ab
​Cerner ​Diphtheria Tetanus Antibody Panel (83269)
​COM ​Diphtheria Tetanus Ab Panel
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)
Pediatric Minimum Volume
(no repeat)
Serum​ ​Serum Separator Tube (SST) ​Red Top Tube (RTT) ​1 mL ​0.8 mL
Specimen Stability Information
Specimen Type Temperature Time
​Serum ​ ​Refrigerated (preferred) ​30 days
​Frozen ​30 days
Rejection Criteria
Gross Hemolysis
Gross ​Lipemia
​Gross Icterus
​Heat Inactivated Specimens
Useful For

Assessment of an antibody response to tetanus and diphtheria toxoid vaccines, which should be performed at least 3 weeks after immunization

Aiding in the evaluation of immunodeficiency

This test should not be used to diagnose tetanus infection 

Test Components
​Diphtheria Toxoid IgG Antibody
Tetanus Toxoid IgG Antibody
Reference Range Information

DIPHTHERIA TOXOID IgG ANTIBODY

Vaccinated: Positive (> or =0.01 IU/mL)

Unvaccinated: Negative (<0.01 IU/mL)

Reference values apply to all ages.

 

TETANUS TOXOID IgG ANTIBODY

Vaccinated: Positive (> or =0.01 IU/mL)

Unvaccinated: Negative (<0.01 IU/mL)

Reference values apply to all ages.

Interpretation

Diphtheria:

Results of 0.01 IU/mL or more suggest a vaccine response.

A diphtheria toxoid booster should be considered for patients with antidiphtheria toxoid IgG values between 0.01 and less than 0.1 IU/mL

Tetanus:

Results of 0.01 IU/mL or more suggest a vaccine response.

A tetanus toxoid booster should strongly be considered for patients with antitetanus toxoid IgG values between 0.01 and 0.5 IU/mL.

Some cases of tetanus, usually mild, have occasionally been observed in patients who have a measurable serum level of 0.01 to 1.0 IU/mL.

For more information visit:
Performing Laboratory Information
Performing Location Day(s) Test Performed Report Available Methodology/Instrumentation
​Mayo Clinic Laboratories Monday through Friday​ ​1 to 4 days
Enzyme-Linked Immunosorbent Assay (ELISA)
Reference Lab
For billing questions, see Contacts
Outreach CPTs
CPT Modifier
(if needed)
Quantity Description Comments
​86317 ​2
Classification

This test should be regarded as 'Research Use Only'. This test has not been cleared or approved by the U.S. Food and Drug Administration. It may not be covered by insurance and providers need to inform all patients of this prior to ordering. 

For Medicare patients, an Advanced Beneficiary notice (ABN) is required; for Medicaid patients, a Noncovered Services Waiver is required, and for commercial payers, prior authorization should be obtained.  

For most current information refer to the Marshfield Laboratory online reference manual.