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23233 Tissue Transglutaminase AB, IgA and IgG

Tissue Transglutaminase AB, IgA and IgG
Test Code: TTGAB
Synonyms/Keywords
tTG Ab, celiac disease, sprue​
Useful For
Tissue Transglutaminase antibodies are useful in the diagnosis of gluten-sensitive enteropathy (Celiac disease). The tTG-IgG assay may aid in the diagnosis of gluten sensitive enteropathy in tTG-IgA negative patients with confirmed IgA deficiency. A negative Tissue Transglutaminase antibody test alone does not rule out gluten-sensitive enteropathy.​
Specimen Requirements
Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)
Pediatric Minimum Volume
(no repeat)
No​ Serum​ Red Top Tube (RTT) or Serum Separator Tube (SST)​ 1.0 mL​ 1.0 mL​ 0.5 mL​
Specimen Stability Information
Specimen Type Temperature Time
Serum​ Refrigerate​ 7 days​
Frozen > 7 days​
Rejection Criteria
Gross lipemia
Gross hemolysis
Heat inactivated samples​
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
Marshfield​ Monday, Wednesday, Friday​ 1 day​ Enzyme Immunoassay (EIA)​
Reference Range Information
Performing Location Reference Range
 Marshfield​ ​
IgG:
< 6.0 U/mL: Negative
6.0 - 9.0 U/mL: Weak Positive
> 9.0 U/mL: Positive​
IgA:
< 4.0 U/mL: Negative
4.0-10.0 U/mL: Weak Positive
> 10.0 U/mL: Positive​
Outreach CPTs
CPT Modifier
(if needed)
Quantity Description Comments
86364 2​ tTG IgG and tTG IgA​
Synonyms/Keywords
tTG Ab, celiac disease, sprue​
Ordering Applications
Ordering Application Description
Centricity ​Tissue Transglut IgA & IgG
​Cerner ​Tissue Transglutaminase Antibody IgA and IgG
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)
Pediatric Minimum Volume
(no repeat)
No​ Serum​ Red Top Tube (RTT) or Serum Separator Tube (SST)​ 1.0 mL​ 1.0 mL​ 0.5 mL​
Specimen Stability Information
Specimen Type Temperature Time
Serum​ Refrigerate​ 7 days​
Frozen > 7 days​
Rejection Criteria
Gross lipemia
Gross hemolysis
Heat inactivated samples​
Useful For
Tissue Transglutaminase antibodies are useful in the diagnosis of gluten-sensitive enteropathy (Celiac disease). The tTG-IgG assay may aid in the diagnosis of gluten sensitive enteropathy in tTG-IgA negative patients with confirmed IgA deficiency. A negative Tissue Transglutaminase antibody test alone does not rule out gluten-sensitive enteropathy.​
Reference Range Information
Performing Location Reference Range
 Marshfield​ ​
IgG:
< 6.0 U/mL: Negative
6.0 - 9.0 U/mL: Weak Positive
> 9.0 U/mL: Positive​
IgA:
< 4.0 U/mL: Negative
4.0-10.0 U/mL: Weak Positive
> 10.0 U/mL: Positive​
For more information visit:
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
Marshfield​ Monday, Wednesday, Friday​ 1 day​ Enzyme Immunoassay (EIA)​
For billing questions, see Contacts
Outreach CPTs
CPT Modifier
(if needed)
Quantity Description Comments
86364 2​ tTG IgG and tTG IgA​
For most current information refer to the Marshfield Laboratory online reference manual.