All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.
This test is not appropriate for acquired hematologic disorders, including the following malignancies: chronic myelocytic leukemia, acute myelocytic leukemia, acute lymphocytic leukemia, chronic lymphocytic leukemia, lymphoma, and leukemia.
This test is not appropriate as a first-tier test for detecting gains or losses of chromosomal material for individuals with intellectual disability, mental retardation, developmental delay, autism, dysmorphic features, birth defects, behavior disorders, learning disability, or cognitive impairment.
-Cell lysis caused by forcing the blood quickly through the needle
-Use of an improper anticoagulant or improperly mixing the blood with the anticoagulant
-Excessive transport time
-Inadequate amount of blood may not permit adequate analysis
-Improper packaging may result in broken, leaky, and contaminated specimen during transport
-Exposure of the specimen to temperature extremes (freezing or >30 degrees C) may kill cells and interfere with attempts to culture cells