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22986 Protein S Antigen, On Coumadin (500530)

Protein S Antigen, On Coumadin (500530)
Test Code: PROT-SM
Synonyms/Keywords
​Protein S Antigen, Protein S Antigen/Factor VII Antigen Ratio
Test Components
​Test includes Protein S antigen, Factor VII antigen, and Prot S/Factor VII ratio.
Specimen Requirements
Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
Pediatric Minimum Volume
Platelet poor plasma​ ​Citrated Blue Top Tube (BTT) ​2 mL ​1 mL
Collection Processing Instructions

Blood should be collected in a blue-top tube containing 3.2% buffered sodium citrate.1 Evacuated collection tubes must be filled to completion to ensure a proper blood to anticoagulant ratio.2,3 The sample should be mixed immediately by gentle inversion at least six times to ensure adequate mixing of the anticoagulant with the blood. Centrifuge and carefully remove the plasma using a plastic transfer pipette, being careful not to disturb the cells. Transfer the plasma into a transfer tube.  Freeze immediately and maintain frozen until tested. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.

Specimen Stability Information
Specimen Type Temperature Time
​Plasma

Freeze at -70 deg C.

(preferable at -70 deg C, but -20 deg C is acceptable for outreach).​

60 days
Rejection Criteria

Gross Hemolysis

​Gross Lipemia
​Thawed
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
LabCorp forwards to Esoterix Tuesday, Friday ​4-7 days ​ELISA
Reference Lab
Reference Range Information
Performing Location Reference Range
​LabCorp forwards to Esoterix Indicated on report​
Outreach CPTs
CPT Modifier
(if needed)
Quantity Description Comments
​85305 ​1 ​Protein S, total
​85230​1​Clotting Factor VII Proconvertin Stable Factor
Synonyms/Keywords
​Protein S Antigen, Protein S Antigen/Factor VII Antigen Ratio
Test Components
​Test includes Protein S antigen, Factor VII antigen, and Prot S/Factor VII ratio.
Ordering Applications
Ordering Application Description
​Centricity ​Protein S Antigen-On Coumadin
​Cerner ​Protein S Antigen-ON Coumadin
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
Pediatric Minimum Volume
Platelet poor plasma​ ​Citrated Blue Top Tube (BTT) ​2 mL ​1 mL
Collection Processing

Blood should be collected in a blue-top tube containing 3.2% buffered sodium citrate.1 Evacuated collection tubes must be filled to completion to ensure a proper blood to anticoagulant ratio.2,3 The sample should be mixed immediately by gentle inversion at least six times to ensure adequate mixing of the anticoagulant with the blood. Centrifuge and carefully remove the plasma using a plastic transfer pipette, being careful not to disturb the cells. Transfer the plasma into a transfer tube.  Freeze immediately and maintain frozen until tested. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.

Specimen Stability Information
Specimen Type Temperature Time
​Plasma

Freeze at -70 deg C.

(preferable at -70 deg C, but -20 deg C is acceptable for outreach).​

60 days
Rejection Criteria

Gross Hemolysis

​Gross Lipemia
​Thawed
Test Components
​Test includes Protein S antigen, Factor VII antigen, and Prot S/Factor VII ratio.
Reference Range Information
Performing Location Reference Range
​LabCorp forwards to Esoterix Indicated on report​
For more information visit:
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
LabCorp forwards to Esoterix Tuesday, Friday ​4-7 days ​ELISA
Reference Lab
For billing questions, see Contacts
Outreach CPTs
CPT Modifier
(if needed)
Quantity Description Comments
​85305 ​1 ​Protein S, total
​85230​1​Clotting Factor VII Proconvertin Stable Factor
For most current information refer to the Marshfield Laboratory online reference manual.