Quantitation of urine normetanephrine (NMN) and metanephrine (MN), collectively referred to as “metanephrines,” together with plasma metanephirne levels is useful as the initial screen to aid in the diagnosis and follow-up of catecholamine-producing tumors, pheochromocytoma and paraganglioma. 24-hr urine is highly recommended.
Biochemical Evaluation and Diagnosis of Catecholamine-producing Tumors
Samples must be in the performing department by 8am on the day of testing for results the same day
Normetanephrine: 50-840 ug/24 hr
Metanephrine: 0-370 ug/24 hr
Reference ranges are based on hypertensive population results