Selenium is quite volatile; therefore, careful specimen collection is necessary to ensure accurate results.
Severe selenium deficiency may contribute to cardiomyopathy.
0-2 months: 45-90 mcg/L
3-6 months: 50-120 mcg/L
7-9 months: 60-120 mcg/L
10-12 months: 70-130 mcg/L
13 months-17 years: 70-150 mcg/L
> or =18 years: 110-165 mcg/L
Selenium accumulates in biological tissue. The normal concentration in adult human blood serum is 110 to 165 mcg/L. Optimal selenium concentration is age dependent (see Reference Values); children require less circulating selenium than adults.
In the state of selenium deficiency associated with loss of glutathione peroxidase activity, the serum concentration is usually below 40 mcg/L.