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22822 Lead, 24 Hour, Urine (PBU)

Lead, 24 Hour, Urine (PBU)
Test Code: LEADUSO
Synonyms/Keywords

Lead (Pb), Pb (Lead) 

Lead, Urine (PBU)

U LEADUSO

Useful For

​Detecting clinically significant lead exposure in 24-hour specimens

This test is not a substitute for blood lead screening

Specimen Requirements
Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
​Urine Clean, plastic urine container with no metal cap or glued insert​ ​ 10 mL​ 2 mL​ ​
Collection Processing Instructions
​1. Collect urine for 24 hours.
2. Refrigerate specimen within 4 hours of completion of 24-hour collection.
Submit sample in a plastic, 10-mL urine tube or a clean, plastic aliquot container with no metal cap or glued insert.
 
Additional Information:
1. 24-Hour volume is required.
2. High concentrations of gadolinium and iodine are known to interfere with most metals tests. If either gadolinium- or iodine-containing contrast media has been administered, a specimen should not be collected for 96 hours.
Specimen Stability Information
Specimen Type Temperature Time
Urine​ ​ ​ Refrigerated (preferred)​ 28 days​
Ambient ​ 28 days​
Frozen​ 28 days​
Rejection Criteria

​All specimens will be evaluated at Mayo Clinic Laboratories for test suitability. 

Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
Mayo Clinic Laboratories​
 Monday through Saturday​
1-4 day​s
Inductively Coupled Plasma-Mass Spectrometry (ICP-MS)​
Reference Lab
Mayo Clinic Laboratories
Reference Range Information
0-17 years:  not established
> or = 18 years:  <2 mcg/24 hour
Interpretation
​

Measurements of urinary lead (Pb) levels have been used to assess lead exposure. However, like lead blood, urinary lead excretion mainly reflects recent exposure and thus shares many of the same limitations for assessing Pb body burden or long-term exposure.

Urinary lead concentration increases exponentially with blood lead and can exhibit relatively high intra-individual variability, even at similar blood lead concentrations.

Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
​83655 ​ ​ ​ ​
Synonyms/Keywords

Lead (Pb), Pb (Lead) 

Lead, Urine (PBU)

U LEADUSO

Ordering Applications
Ordering Application Description
COM Lead, 24 hr Urine (PBU)
​Cerner ​Lead, Urine (PBU)
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
​Urine Clean, plastic urine container with no metal cap or glued insert​ ​ 10 mL​ 2 mL​ ​
Collection Processing
​1. Collect urine for 24 hours.
2. Refrigerate specimen within 4 hours of completion of 24-hour collection.
Submit sample in a plastic, 10-mL urine tube or a clean, plastic aliquot container with no metal cap or glued insert.
 
Additional Information:
1. 24-Hour volume is required.
2. High concentrations of gadolinium and iodine are known to interfere with most metals tests. If either gadolinium- or iodine-containing contrast media has been administered, a specimen should not be collected for 96 hours.
Specimen Stability Information
Specimen Type Temperature Time
Urine​ ​ ​ Refrigerated (preferred)​ 28 days​
Ambient ​ 28 days​
Frozen​ 28 days​
Rejection Criteria

​All specimens will be evaluated at Mayo Clinic Laboratories for test suitability. 

Useful For

​Detecting clinically significant lead exposure in 24-hour specimens

This test is not a substitute for blood lead screening

Reference Range Information
0-17 years:  not established
> or = 18 years:  <2 mcg/24 hour
Interpretation
​

Measurements of urinary lead (Pb) levels have been used to assess lead exposure. However, like lead blood, urinary lead excretion mainly reflects recent exposure and thus shares many of the same limitations for assessing Pb body burden or long-term exposure.

Urinary lead concentration increases exponentially with blood lead and can exhibit relatively high intra-individual variability, even at similar blood lead concentrations.

For more information visit:
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
Mayo Clinic Laboratories​
 Monday through Saturday​
1-4 day​s
Inductively Coupled Plasma-Mass Spectrometry (ICP-MS)​
Reference Lab
Mayo Clinic Laboratories
For billing questions, see Contacts
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
​83655 ​ ​ ​ ​
For most current information refer to the Marshfield Laboratory online reference manual.