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22698 Mercury, 24 Hour, Urine (HGU)

Mercury, 24 Hour, Urine (HGU)
Test Code: MERCUSO
Synonyms/Keywords
Hg (Mercury), Mercury (Hg)
Useful For
​Detecting mercury toxicity
Specimen Requirements
Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)
Pediatric Minimum Volume
(no repeat)
​Urine Clean, plastic urine container with no metal cap or glued insert​ 10 mL​ 2 mL​
Collection Processing Instructions
1. Collect urine for 24 hours.
2. Refrigerate specimen within 4 hours of completion of 24-hour collection.
3. Submit sample in a plastic, 10-mL urine tube or a clean, plastic aliquot container with no metal cap or glued insert.
 
Additional Information:
24-Hour volume is required.
High concentrations of gadolinium and iodine are known to interfere with most metals tests. If either gadolinium- or iodine-containing contrast media has been administered, a specimen should not be collected for 96 hours.​
Specimen Stability Information
Specimen Type Temperature Time
Urine​ ​ Refrigerated (preferred)​ 7 days​
Frozen ​ 7 days​
Rejection Criteria

​All specimens will be evaluated at Mayo Clinic Laboratories for test suitability. 

Interference

​To avoid contamination by dust, specimen should be collected away from the site of suspected exposure.

Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
Mayo Clinic Laboratories
Monday through Saturday​
1-4 day​
Inductively Coupled Plasma-Mass Spectrometry (ICP-MS)​
Reference Lab
Test Information

​The correlation between the levels of mercury (Hg) excretion in the urine and the clinical symptoms is considered poor.

It had always been thought that urine was a more appropriate marker of inorganic mercury, because organic mercury represented only a small fraction of urinary mercury. Based on possible demethylation of methylmercury within the body, urine may represent a mixture of dietary methylmercury and inorganic mercury. Seafood consumption can contribute to urinary mercury levels (up to 30%), which is consistent with the suggestion that due to demethylation processes in the human body, a certain proportion of urinary mercury can originate from dietary consumption of fish/seafood.

Reference Range Information

​0-17 years: Not established.
>= 18 years: <2 mcg/24 hour
Toxic concentration: >50 mcg/24 hour

The concentration at which toxicity is expressed is widely variable between patients. 50 mcg/24 hour is the lowest concentration at which toxicity is usually apparent.

Interpretation
​Daily urine excretion of mercury above 50 mcg/day indicates significant exposure (per World Health Organization standard).
Outreach CPTs
CPT Modifier
(if needed)
Quantity Description Comments
​83825
Synonyms/Keywords
Hg (Mercury), Mercury (Hg)
Ordering Applications
Ordering Application Description
​Centricity ​Mercury-24hr
​Cerner ​Mercury Level 24 Hour Urine (8592)
​COM ​Mercury, 24 Hr Urine
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)
Pediatric Minimum Volume
(no repeat)
​Urine Clean, plastic urine container with no metal cap or glued insert​ 10 mL​ 2 mL​
Collection Processing
1. Collect urine for 24 hours.
2. Refrigerate specimen within 4 hours of completion of 24-hour collection.
3. Submit sample in a plastic, 10-mL urine tube or a clean, plastic aliquot container with no metal cap or glued insert.
 
Additional Information:
24-Hour volume is required.
High concentrations of gadolinium and iodine are known to interfere with most metals tests. If either gadolinium- or iodine-containing contrast media has been administered, a specimen should not be collected for 96 hours.​
Specimen Stability Information
Specimen Type Temperature Time
Urine​ ​ Refrigerated (preferred)​ 7 days​
Frozen ​ 7 days​
Rejection Criteria

​All specimens will be evaluated at Mayo Clinic Laboratories for test suitability. 

Interference

​To avoid contamination by dust, specimen should be collected away from the site of suspected exposure.

Useful For
​Detecting mercury toxicity
Reference Range Information

​0-17 years: Not established.
>= 18 years: <2 mcg/24 hour
Toxic concentration: >50 mcg/24 hour

The concentration at which toxicity is expressed is widely variable between patients. 50 mcg/24 hour is the lowest concentration at which toxicity is usually apparent.

Interpretation
​Daily urine excretion of mercury above 50 mcg/day indicates significant exposure (per World Health Organization standard).
For more information visit:
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
Mayo Clinic Laboratories
Monday through Saturday​
1-4 day​
Inductively Coupled Plasma-Mass Spectrometry (ICP-MS)​
Reference Lab
For billing questions, see Contacts
Outreach CPTs
CPT Modifier
(if needed)
Quantity Description Comments
​83825
For most current information refer to the Marshfield Laboratory online reference manual.