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22639 Folate, Serum

Folate, Serum
Test Code: FOL
Synonyms/Keywords
​Folate- Folic Acid​
Specimen Requirements

Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
No​ ​​
 Plasma/Serum​ Lithium Heparin Plasma Separator Tube (PST)
 ​Lithium Heparin Green Top Tube (GTT), ​​Serum Separator Tube (SST), Red Top Tube (RTT)
 1 mL​ 0.5 mL​ 0.3 mL​
  • GTT/RTT - physically separate plasma or serum from contact with cells as soon as possible of before transport.  Separate from cells within 30 minutes to minimize uptake of corticosteroids by RBCs
Collection Processing Instructions
​High doses of exogenous biotin (also termed Vitamin B7, Vitamin H or Coenzyme R) may interfere with this assay. It is recommended that patients refrain from consuming any multivitamin or supplement containing biotin for at least 72 hours prior to collection of a blood sample.
Specimen Stability Information

Specimen Type Temperature Time
Plasma/Serum​ Ambient​ 4 hours​
Refrigerated​ 2 days​
Frozen​ 6 months​

  • Thaw samples only once
Rejection Criteria
Trace Hemolysis
Marked Icterus
Interference

Human Anti-Murine Antibodies (HAMA) may develop leading to test interference in patients receiving murine-based agents for chemotherapy or tumor-imaging studies. Likewise, Fluorescein used in retinal angiography will interfere.​

High doses of exogenous biotin (also termed Vitamin B7, Vitamin H or Coenzyme R) may interfere with this assay.
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
Weston​ ​Monday through Sunday​ ​Less than 2 hours​ ​Homogenous Sandwich Chemiluminescent Immunoassay/Siemens Dimension Vista
Marshfield​ Monday through Sunday​ Less than 2 hours​
 Beckman Coulter DXI
Reference Range Information
Performing Location Reference Range
Weston
 >= 4.0 ng/mL  ​
​Marshfield ​>= 5.9 ng/mL
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
82746​ ​ ​ ​ ​
Synonyms/Keywords
​Folate- Folic Acid​
Ordering Applications
Ordering Application Description
​Cerner
 ​Folate Level

​

If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements

Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
No​ ​​
 Plasma/Serum​ Lithium Heparin Plasma Separator Tube (PST)
 ​Lithium Heparin Green Top Tube (GTT), ​​Serum Separator Tube (SST), Red Top Tube (RTT)
 1 mL​ 0.5 mL​ 0.3 mL​
  • GTT/RTT - physically separate plasma or serum from contact with cells as soon as possible of before transport.  Separate from cells within 30 minutes to minimize uptake of corticosteroids by RBCs
Collection Processing
​High doses of exogenous biotin (also termed Vitamin B7, Vitamin H or Coenzyme R) may interfere with this assay. It is recommended that patients refrain from consuming any multivitamin or supplement containing biotin for at least 72 hours prior to collection of a blood sample.
Specimen Stability Information

Specimen Type Temperature Time
Plasma/Serum​ Ambient​ 4 hours​
Refrigerated​ 2 days​
Frozen​ 6 months​

  • Thaw samples only once
Rejection Criteria
Trace Hemolysis
Marked Icterus
Interference

Human Anti-Murine Antibodies (HAMA) may develop leading to test interference in patients receiving murine-based agents for chemotherapy or tumor-imaging studies. Likewise, Fluorescein used in retinal angiography will interfere.​

High doses of exogenous biotin (also termed Vitamin B7, Vitamin H or Coenzyme R) may interfere with this assay.
Reference Range Information
Performing Location Reference Range
Weston
 >= 4.0 ng/mL  ​
​Marshfield ​>= 5.9 ng/mL
For more information visit:
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
Weston​ ​Monday through Sunday​ ​Less than 2 hours​ ​Homogenous Sandwich Chemiluminescent Immunoassay/Siemens Dimension Vista
Marshfield​ Monday through Sunday​ Less than 2 hours​
 Beckman Coulter DXI
For billing questions, see Contacts
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
82746​ ​ ​ ​ ​
For most current information refer to the Marshfield Laboratory online reference manual.