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Lab Test Reference Manual
Human Reference Manual
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22418
Lab Test Reference Manual
Human Reference Manual
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22418
Ceruloplasmin
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Ceruloplasmin
Test Code: CERULO
Overview
Ordering
Specimen
Performing
Clinical/Interpretive
Contacts
Coding
Synonyms/Keywords
Synonyms, Keywords
Copper Oxidase
Useful For
Useful For
This test is useful for monitoring ceruloplasmin levels in blood. Decreased levels are primarily of interest in the diagnosis of Wilson's disease. Decreased levels are also seen in primary biliary cirrhosis and in GI disorders where copper uptake is impaired. Ceruloplasmin, and acute phase reactant, is increased in inflammatory disorders when estrogen levels are high, with malignant tumors, and acute leukemia.
Specimen Requirements
Specimen Requirements
Fasting Required
Specimen Type
Preferred Container/Tube
Acceptable Container/Tube
Specimen Volume
Specimen Minimum Volume
(allows for 1 repeat)
Pediatric Minimum Volume
(no repeat)
No
Serum
Red Top Tube (RTT)
Serum Separator Tube (SST)
0.5 mL
0.4 mL
0.3 mL
Collection Processing Instructions
Collection Processing
Separate serum from cells within 2 hours of collection.
Specimen Stability Information
Specimen Stability Information
Specimen Type
Temperature
Time
Serum
Refrigerate
7 days
Frozen
3 months
Rejection Criteria
Rejection Criteria
Plasma samples
Performing Laboratory Information
Performing Laboratory Information
Performing Location
Day(s) Test Performed
Analytical Time
Methodology/Instrumentation
Marshfield
Monday- Friday
6-8 hours
Turbidimetric method/The Binding Site Optilite analyzer
Test Information
Test Information
Oral contraceptives or estrogen will increase ceruloplasmin levels.
Reference Range Information
Reference Range Information
Performing Location
Reference Range
Marshfield
20-60 mg/dL
Interpretation
Interpretations
Decreased ceruloplasmin levels may be seen in primary biliary cirrhosis and in GI disorders where copper uptake is impaired. Decreased levels are primarily of interest in the diagnosis of Wilson's Disease, also known as hepatolenticular degeration. This involves a defect in ceruloplasmin synthesis and results in excessive accumulation of copper in various body tissues - liver, cornea and brain tissue.
Outreach CPTs
Outreach CPT Codes
CPT
Modifier
(if needed)
Quantity
Description
Comments
82390
Synonyms/Keywords
Synonyms, Keywords
Copper Oxidase
Ordering Applications
Ordering Applications
Ordering Application
Description
Cerner
Ceruloplasmin
COM
Ceruloplasmin
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
Specimen Requirements
Fasting Required
Specimen Type
Preferred Container/Tube
Acceptable Container/Tube
Specimen Volume
Specimen Minimum Volume
(allows for 1 repeat)
Pediatric Minimum Volume
(no repeat)
No
Serum
Red Top Tube (RTT)
Serum Separator Tube (SST)
0.5 mL
0.4 mL
0.3 mL
Collection Processing
Collection Processing
Separate serum from cells within 2 hours of collection.
Specimen Stability Information
Specimen Stability Information
Specimen Type
Temperature
Time
Serum
Refrigerate
7 days
Frozen
3 months
Rejection Criteria
Rejection Criteria
Plasma samples
Useful For
Useful For
This test is useful for monitoring ceruloplasmin levels in blood. Decreased levels are primarily of interest in the diagnosis of Wilson's disease. Decreased levels are also seen in primary biliary cirrhosis and in GI disorders where copper uptake is impaired. Ceruloplasmin, and acute phase reactant, is increased in inflammatory disorders when estrogen levels are high, with malignant tumors, and acute leukemia.
Reference Range Information
Reference Range Information
Performing Location
Reference Range
Marshfield
20-60 mg/dL
Interpretation
Interpretations
Decreased ceruloplasmin levels may be seen in primary biliary cirrhosis and in GI disorders where copper uptake is impaired. Decreased levels are primarily of interest in the diagnosis of Wilson's Disease, also known as hepatolenticular degeration. This involves a defect in ceruloplasmin synthesis and results in excessive accumulation of copper in various body tissues - liver, cornea and brain tissue.
For more information visit:
http://labtestsonline.org
Performing Laboratory Information
Performing Laboratory Information
Performing Location
Day(s) Test Performed
Analytical Time
Methodology/Instrumentation
Marshfield
Monday- Friday
6-8 hours
Turbidimetric method/The Binding Site Optilite analyzer
For billing questions, see Contacts
Outreach CPTs
Outreach CPT Codes
CPT
Modifier
(if needed)
Quantity
Description
Comments
82390
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For most current information refer to the Marshfield Laboratory online reference manual.