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22467 Copper, Serum

Copper, Serum
Test Code: COP
Synonyms/Keywords
Cu, Copper, Copper in serum, Copper in blood​
Useful For
This test is useful for monitoring copper level in serum​
Specimen Requirements
Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
No​ Serum​
Royal Blue Top Tube
(RBTT)​
Red Top Tube
(RTT)
 
Lithium-Heparin Green Top Tube
(GTT)
 
Royal Blue K2 EDTA Tube
​
 2.0 mL serum​ 1.1 mL serum​ 1.0 mL serum​
Collection Processing Instructions

Sample collection instructions:

          1.      Centrifuge the sample

          2.      Within 2 hours of collection: Pour off, or aliquot using plastic pipet, serum into "Serum Transfer Tube" or alternate metal-free aliquot tube (example: "Mayo Metal-Free Plastic Aliquot Vial") (do not use glass pipettes, etc.)

 

Important Notes / Information: Serum or plasma should be removed from the cells within 2 hours of collection. Do not use glass pipettes or aliquot tubes, rubber stoppers, wood applicator sticks (for rimming clots), etc. as these may contaminate the specimen! If absolute necessary to rim for clots, only use a plastic pipet to minimize potential sample contamination.  All collection and transfer tubes can be requested/ordered from Marshfield Labs.

Marshfield Labs serum transfer tubes have been validated to be metal-free and can be used for this test.

Specimen Stability Information
Specimen Type Temperature Time
Serum​ Refrigerate​ 1 week​
Frozen 1 month​
Rejection Criteria
Gel or serum separator tubes
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
Marshfield​ Monday, Wednesday, Friday​ 6-8 hours​ Atomic Absorption/Perkin-Elmer 3100 Atomic Absorption Analyzer​
Test Information
This test was developed and its performance characteristics determined by Marshfield Labs.  It has not been cleared or approved by the US Food and Drug Administration.  This test is used for clinical purposes.  It should not be regarded as investigational or for research.
Reference Range Information
Performing Location Reference Range
Marshfield​

0-6 months of age: 0-70 ug/dL

6 months - 5 years: 27-153 ug/dL

Males >5 years: 80-151 ug/dL

Females >5 years: 88-183 ug/dL​

Interpretation
Copper in serum is found in association with ceruloplasmin and alpha-globulin, and changes in the concentration of copper will be reflected in changes in ceruloplasmin level.  Copper deficiency may be observed in infants due to prematurity, malnutrition, malabsorption, chronic diarrhea, hyperalimentation, and prolonged milk diet.  Decreased serum levels are also seen in Wilson's Disease due to copper accumulating in the liver, brain, kidney and cornea.​
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
82525​ ​ ​ ​ ​
Classification
This test was developed and its performance characteristics determined by Marshfield Labs.  It has not been cleared or approved by the US Food and Drug Administration.  This test is used for clinical purposes.  It should not be regarded as investigational or for research.
Synonyms/Keywords
Cu, Copper, Copper in serum, Copper in blood​
Ordering Applications
Ordering Application Description
​Centricity ​Copper
​Cerner ​Copper Level
​COM ​Copper - Blood
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
No​ Serum​
Royal Blue Top Tube
(RBTT)​
Red Top Tube
(RTT)
 
Lithium-Heparin Green Top Tube
(GTT)
 
Royal Blue K2 EDTA Tube
​
 2.0 mL serum​ 1.1 mL serum​ 1.0 mL serum​
Collection Processing

Sample collection instructions:

          1.      Centrifuge the sample

          2.      Within 2 hours of collection: Pour off, or aliquot using plastic pipet, serum into "Serum Transfer Tube" or alternate metal-free aliquot tube (example: "Mayo Metal-Free Plastic Aliquot Vial") (do not use glass pipettes, etc.)

 

Important Notes / Information: Serum or plasma should be removed from the cells within 2 hours of collection. Do not use glass pipettes or aliquot tubes, rubber stoppers, wood applicator sticks (for rimming clots), etc. as these may contaminate the specimen! If absolute necessary to rim for clots, only use a plastic pipet to minimize potential sample contamination.  All collection and transfer tubes can be requested/ordered from Marshfield Labs.

Marshfield Labs serum transfer tubes have been validated to be metal-free and can be used for this test.

Specimen Stability Information
Specimen Type Temperature Time
Serum​ Refrigerate​ 1 week​
Frozen 1 month​
Rejection Criteria
Gel or serum separator tubes
Useful For
This test is useful for monitoring copper level in serum​
Reference Range Information
Performing Location Reference Range
Marshfield​

0-6 months of age: 0-70 ug/dL

6 months - 5 years: 27-153 ug/dL

Males >5 years: 80-151 ug/dL

Females >5 years: 88-183 ug/dL​

Interpretation
Copper in serum is found in association with ceruloplasmin and alpha-globulin, and changes in the concentration of copper will be reflected in changes in ceruloplasmin level.  Copper deficiency may be observed in infants due to prematurity, malnutrition, malabsorption, chronic diarrhea, hyperalimentation, and prolonged milk diet.  Decreased serum levels are also seen in Wilson's Disease due to copper accumulating in the liver, brain, kidney and cornea.​
For more information visit:
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
Marshfield​ Monday, Wednesday, Friday​ 6-8 hours​ Atomic Absorption/Perkin-Elmer 3100 Atomic Absorption Analyzer​
For billing questions, see Contacts
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
82525​ ​ ​ ​ ​
Classification
This test was developed and its performance characteristics determined by Marshfield Labs.  It has not been cleared or approved by the US Food and Drug Administration.  This test is used for clinical purposes.  It should not be regarded as investigational or for research.
For most current information refer to the Marshfield Laboratory online reference manual.