Iodine/Creatinine Ratio, Random, Urine, ICRUSO, U ICRUSO, Iodine Creatinine Ratio, Random Urine (ICRU), Iodine Excretion, Urinary Free Iodine, Urinary Iodine, IODCU
Assessment of iodine toxicity or recent iodine exposure in a random urine collection
Monitoring iodine excretion reate as index of replacement therapy
Patient Preparation: High concentrations of gadolinium and iodine are known to interfere with most metal tests. If either gadolinium- or iodine-containing contrast media has been administered, wait a minimum of 96 hours before starting collection.
All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.
Administration of iodine-based contrast media and drugs containing iodine, such as amiodarone, will yield elevated results.
IODC: Iductively Coupled Plasma Mass Spectrometry (ICP-MS)
CRETR: Enzymatic Colorimetric Assay
Iodine is an essential element for thyroid hormone production.
The measurement of urinary iodine is preferred for assessment of toxicity, recent exposure, and monitoring iodine excretion rate as an index of replacement therapy.
0-17 Years: not established
> or = 18 Years: <584 mcg/g creatinine
Measurement of urinary iodine excretion provides the best index of dietary iodine intake and deficiency is generally indicated when the concentrations are below 100 mcg/L. For deficiency, 10 repeat random urines are recommended.
World Healthcare Organization (WHO) Criteria for Assessing Iodine Status(1)
Children >6 years old and adults:
Lactating women and children <2 years old: