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26331 Cold Agglutinin Titer, Serum (CATR)

Cold Agglutinin Titer, Serum (CATR)
Test Code: CATRSO
Synonyms/Keywords

​CATR, Cold Agglutinin Titer, Cryoagglutinin

Useful For

​Detection of cold agglutinins in patients with suspected cold agglutinin disease.

Specimen Requirements
Specimen TypePreferred Container/TubeAcceptable Container/TubeSpecimen VolumeSpecimen Minimum Volume
(allows for 1 repeat)
Pediatric Minimum Volume
(no repeat)
​Serum Red​Red Top Tube (RTT)​4 mL​1 mL​1 mL
Collection Processing Instructions

1.     Use a warm pack to keep specimen at 37 degrees C prior to and after collecting.

2.     Allow specimens to clot at 37 degrees C.

3.     Centrifuge at 37 degrees C and separate serum from red cells immediately after blood clots, or within one hour of collection.

4.     Do not refrigerate prior to separation of serum from red cells.

Specimen Stability Information
Specimen TypeTemperature
​Serum Red ​ ​​Refrigerated (preferred)
​Ambient
​Frozen
Rejection Criteria
All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.
Interference

​Normal individuals may have low levels of cold agglutinins. 

Performing Laboratory Information
Performing LocationDay(s) Test PerformedReport AvailableMethodology/Instrumentation
​Mayo Clinic Laboratories​Monday through Friday, Sunday​1 to 3 days​Titration-Red Cell Agglutination at 4 Degrees C
Reference Lab
Reference Range Information
Performing LocationReference Range
​Mayo Clinic Laboratories​<1:64
Interpretation

​Patients with cold agglutinin syndrome usually exhibit a titer value greater than 1:512, with rare cases reportedly as low as 1:64.

Normal individuals often have low levels of cold agglutinins.

The test is not a direct measure of clinical significance and must be used in conjunction with other in vitro and in vivo parameters.

Outreach CPTs
CPTModifier
(if needed)
QuantityDescriptionComments
​86157
Synonyms/Keywords

​CATR, Cold Agglutinin Titer, Cryoagglutinin

Ordering Applications
Ordering ApplicationDescription
​Cerner​Cold Agglutinin Titer (CATR)
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
Specimen TypePreferred Container/TubeAcceptable Container/TubeSpecimen VolumeSpecimen Minimum Volume
(allows for 1 repeat)
Pediatric Minimum Volume
(no repeat)
​Serum Red​Red Top Tube (RTT)​4 mL​1 mL​1 mL
Collection Processing

1.     Use a warm pack to keep specimen at 37 degrees C prior to and after collecting.

2.     Allow specimens to clot at 37 degrees C.

3.     Centrifuge at 37 degrees C and separate serum from red cells immediately after blood clots, or within one hour of collection.

4.     Do not refrigerate prior to separation of serum from red cells.

Specimen Stability Information
Specimen TypeTemperature
​Serum Red ​ ​​Refrigerated (preferred)
​Ambient
​Frozen
Rejection Criteria
All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.
Interference

​Normal individuals may have low levels of cold agglutinins. 

Useful For

​Detection of cold agglutinins in patients with suspected cold agglutinin disease.

Reference Range Information
Performing LocationReference Range
​Mayo Clinic Laboratories​<1:64
Interpretation

​Patients with cold agglutinin syndrome usually exhibit a titer value greater than 1:512, with rare cases reportedly as low as 1:64.

Normal individuals often have low levels of cold agglutinins.

The test is not a direct measure of clinical significance and must be used in conjunction with other in vitro and in vivo parameters.

For more information visit:
Performing Laboratory Information
Performing LocationDay(s) Test PerformedReport AvailableMethodology/Instrumentation
​Mayo Clinic Laboratories​Monday through Friday, Sunday​1 to 3 days​Titration-Red Cell Agglutination at 4 Degrees C
Reference Lab
For billing questions, see Contacts
Outreach CPTs
CPTModifier
(if needed)
QuantityDescriptionComments
​86157
For most current information refer to the Marshfield Laboratory online reference manual.