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26187 Ethyl Glucuronide Screen w/Reflex (ETGR)

Ethyl Glucuronide Screen w/Reflex (ETGR)
Test Code: ETGRSO
Synonyms/Keywords

​Alcohol biomarkers

Test Components

​Testing begins with a screening assay.  If the screen is positive, then the liquid chromaography-tandem mass spectrometry confirmation with quantification will be performed at an additional charge. 

Useful For

​Screening for drug abuse involving alcohol.

Specimen Requirements
Fasting RequiredSpecimen TypePreferred Container/TubeAcceptable Container/TubeSpecimen VolumeSpecimen Minimum Volume
(allows for 1 repeat)
Pediatric Minimum Volume
(no repeat)
​NoRandom ​Urine​Sterile screw capped container (e.g. Sage cup)​20 mL​2.5 mL
Collection Processing Instructions

1. ​Collect a random urine specimen.

2. Submit 20 mL in 1 container.

3. No preservative.

Specimen Stability Information
Specimen TypeTemperatureTime
​Urine ​ ​​Refrigerated (preferred)​28 days
​Frozen​28 days
​Ambient​72 hours
Interference

​Care should be taken when interpreting results since there are many factors (eg, fluid intake and other biologic factors) that may influence a urine test result. It is possible that substances other than those investigated in the specificity study may interfere with the test and cause false-positive or negative results.

Performing Laboratory Information
Performing LocationDay(s) Test PerformedAnalytical TimeMethodology/Instrumentation
​Mayo Clinic Laboratories​Monday through Sunday​1 day

​Immunoassay

LC-MS/MS Confirmation (as needed)

Reference Lab
Test Information

​This procedure uses immunoassay reagents that are designed to produce a negative result when no drugs are present in a natural (ie, unadulterated) specimen of urine; the assay is designed to have a high true-negative rate. Like all immunoassays, it can have a false-positive rate due to cross-reactivity with natural chemicals and drugs other than those they were designed to detect. The immunoassay also has a false-negative rate to the antibody’s ability to cross-react with different drugs in the class being screened for.

Ethyl glucuronide is a direct metabolite of ethanol that is formed by enzymatic conjugation of ethanol with glucuronic acid. Alcohol in urine is normally detected for only a few hours, whereas ethyl glucuronide can be detected in the urine for 1 to 3 days.

Reference Range Information
Performing LocationReference Range
​Mayo Clinic Laboratories

​Negative

Screening cutoff concentration:

Ethyl Glucuronide:  500 ng/mL

Interpretation

​This assay only provides a preliminary analytical test result. A more specific alternative method (ie, liquid chromatography-tandem mass spectrometry; LC-MS/MS) must be used to obtain a confirmed analytical result. A positive result using the ethyl glucuronide screen indicates only the potential presence of ethyl glucuronide and does not necessarily correlate with the extent of physiological and psychological effects.

Outreach CPTs
CPTModifier
(if needed)
QuantityDescriptionComments
​80307​1​Screen
​80321​1​Confirmation (as needed)
Synonyms/Keywords

​Alcohol biomarkers

Test Components

​Testing begins with a screening assay.  If the screen is positive, then the liquid chromaography-tandem mass spectrometry confirmation with quantification will be performed at an additional charge. 

Ordering Applications
Ordering ApplicationDescription
​Centricity​Ethyl Glucuronide Screen w/Reflex (ETGR)
​COM​Ethyl Glucuronide Screen
​Cerner​Ethyl Gluc Scr w/Ref (ETGR)
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
Fasting RequiredSpecimen TypePreferred Container/TubeAcceptable Container/TubeSpecimen VolumeSpecimen Minimum Volume
(allows for 1 repeat)
Pediatric Minimum Volume
(no repeat)
​NoRandom ​Urine​Sterile screw capped container (e.g. Sage cup)​20 mL​2.5 mL
Collection Processing

1. ​Collect a random urine specimen.

2. Submit 20 mL in 1 container.

3. No preservative.

Specimen Stability Information
Specimen TypeTemperatureTime
​Urine ​ ​​Refrigerated (preferred)​28 days
​Frozen​28 days
​Ambient​72 hours
Interference

​Care should be taken when interpreting results since there are many factors (eg, fluid intake and other biologic factors) that may influence a urine test result. It is possible that substances other than those investigated in the specificity study may interfere with the test and cause false-positive or negative results.

Useful For

​Screening for drug abuse involving alcohol.

Test Components

​Testing begins with a screening assay.  If the screen is positive, then the liquid chromaography-tandem mass spectrometry confirmation with quantification will be performed at an additional charge. 

Reference Range Information
Performing LocationReference Range
​Mayo Clinic Laboratories

​Negative

Screening cutoff concentration:

Ethyl Glucuronide:  500 ng/mL

Interpretation

​This assay only provides a preliminary analytical test result. A more specific alternative method (ie, liquid chromatography-tandem mass spectrometry; LC-MS/MS) must be used to obtain a confirmed analytical result. A positive result using the ethyl glucuronide screen indicates only the potential presence of ethyl glucuronide and does not necessarily correlate with the extent of physiological and psychological effects.

For more information visit:
Performing Laboratory Information
Performing LocationDay(s) Test PerformedAnalytical TimeMethodology/Instrumentation
​Mayo Clinic Laboratories​Monday through Sunday​1 day

​Immunoassay

LC-MS/MS Confirmation (as needed)

Reference Lab
For billing questions, see Contacts
Outreach CPTs
CPTModifier
(if needed)
QuantityDescriptionComments
​80307​1​Screen
​80321​1​Confirmation (as needed)
For most current information refer to the Marshfield Laboratory online reference manual.