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25245 Anser ADA, Prometheus (3170)

Anser ADA, Prometheus (3170)
Test Code: PADASO
Synonyms/Keywords
​Adalimumab
Test Components

​Anser ADA measures serum adalimumab (ADA) levels and antibodies to adalimumab (ATA).

Useful For

Serum concentrations of adalimumab (ADA) may vary among equally dosed patients which can ultimately affect patient outcomes.  Suboptimal levels of ADA have been lined to lower response rates in IBD patients.  Furthermore, some patients may develop immunogenicity to ADA by producing antibodies to adalimumab (ATA).  The presence of ATA has also been associated with increased rates of infusion reasctions and drug clearance leading to lower response rates.  Therefore, the quantitative measurement of ADA and ATA levels in serum provides valuable information to help them gain a better understanding of the factors that may be affecting a patient's loss of response. 

The Anser ADA test is a next generation quantitative monitoring assay that allows for measurement and monitoring serum ADA and ATA levels at anytime during therapy. 

Specimen Requirements
Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)
Pediatric Minimum Volume
(no repeat)
​No ​Serum ​Serum Separator Tube (SST) ​Red Top Tube (RTT) ​2.0 mL ​0.5 mL
Specimen Stability Information
Specimen Type Temperature Time
​Serum ​ ​Ambient 7 days
​Refrigerate 9 days
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
​Prometheus Labs ​Monday through Friday ​3 days ​Nonradio-labeled liquid-phase mobility shift assays
Reference Lab
Reference Range Information

Serum adalimumab (ADA) concentration: <1.6 ug/mL

Antibody to adalimumab (ATA) concentration: <1.7 U/mL

Synonyms/Keywords
​Adalimumab
Test Components

​Anser ADA measures serum adalimumab (ADA) levels and antibodies to adalimumab (ATA).

Ordering Applications
Ordering Application Description
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)
Pediatric Minimum Volume
(no repeat)
​No ​Serum ​Serum Separator Tube (SST) ​Red Top Tube (RTT) ​2.0 mL ​0.5 mL
Specimen Stability Information
Specimen Type Temperature Time
​Serum ​ ​Ambient 7 days
​Refrigerate 9 days
Useful For

Serum concentrations of adalimumab (ADA) may vary among equally dosed patients which can ultimately affect patient outcomes.  Suboptimal levels of ADA have been lined to lower response rates in IBD patients.  Furthermore, some patients may develop immunogenicity to ADA by producing antibodies to adalimumab (ATA).  The presence of ATA has also been associated with increased rates of infusion reasctions and drug clearance leading to lower response rates.  Therefore, the quantitative measurement of ADA and ATA levels in serum provides valuable information to help them gain a better understanding of the factors that may be affecting a patient's loss of response. 

The Anser ADA test is a next generation quantitative monitoring assay that allows for measurement and monitoring serum ADA and ATA levels at anytime during therapy. 

Test Components

​Anser ADA measures serum adalimumab (ADA) levels and antibodies to adalimumab (ATA).

Reference Range Information

Serum adalimumab (ADA) concentration: <1.6 ug/mL

Antibody to adalimumab (ATA) concentration: <1.7 U/mL

For more information visit:
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
​Prometheus Labs ​Monday through Friday ​3 days ​Nonradio-labeled liquid-phase mobility shift assays
Reference Lab
For billing questions, see Contacts
For most current information refer to the Marshfield Laboratory online reference manual.