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24932 Pancreatic Elastase, Fecal (123234)

Pancreatic Elastase, Fecal (123234)
Test Code: PE1SO
Synonyms/Keywords
PE1​, Elactase, Pancreatic, ST PE1SO, Pancreatic Elastase, Fecal (123134)
Useful For
Diagnosis or the exclusion of exocrine pancreatic insufficiency, which may be associated with chronic pancreatitis, cystic fibrosis, carcinoma of the pancreas, diabetes mellitus type 1 (insulin-dependent diabetes mellitus), Shwachman-Diamond syndrome, and other etiologies of pancreatic insufficiency.
Specimen Requirements
 
Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
​Stool (unpreserved, random)

​Sage container

 (screw-capped plastic vial)

​Sterile container ​3 grams ​1 gram (This volume does not allow for repeat testing)
Collection Processing Instructions
Do not contaminate outside of container. Do not overfill container. Do not submit watery or unformed (loose) stool. Do not use a preservative.  Specimens should be transported refrigerated (ice packs) or frozen if transport temperature is expected to exceed 40°C (104°F).
Specimen Stability Information
Specimen Type Temperature Time
​Stool ​ ​ ​Ambient ​14 days
​Refrigerate ​14 days
​Frozen 14 days
​Freeze/thaw cycles​Stable x 3
Rejection Criteria
​Serum or plasma received
​Stool contaminated with urine
​Watery or unformed (loose) stool
​Preserved stool
Performing Laboratory Information
Performing Location Analytical Time​Methodology/Instrumentation
LabCorp ​4-6 days​Enzyme-linked immunosorbent assay (ELISA) based upon a monoclonal antibody-based detection system specific for pancreatic elastase-1 (PEL-1)
Reference Lab
Test Information
The polyclonal antibodies used in this assay are specifically directed against defined sequences of the human pancreatic elastase molecule. The enzyme stability is remarkably high despite its proteolytic activity, as elastase is found in feces in about a sixfold concentration as in pancreatic fluid. The determination of enzyme concentration in feces reflects the exocrine secretory capacity of the pancreas.
Reference Range Information
• Normal: >200 μg elastase/g fecal material
• Moderate pancreatic insufficiency: 100−200 μg elastase/g fecal material
• Severe pancreatic insufficiency: <100 μg elastase/g fecal material
Outreach CPTs
CPT Modifier
(if needed)
Quantity Description Comments
86253
Synonyms/Keywords
PE1​, Elactase, Pancreatic, ST PE1SO, Pancreatic Elastase, Fecal (123134)
Ordering Applications
Ordering Application Description
​Cerner ​Pancreatic Elastase, Fecal (123234)
​COM ​Pancreatic Elactase, Fecal (123234)
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
 
Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
​Stool (unpreserved, random)

​Sage container

 (screw-capped plastic vial)

​Sterile container ​3 grams ​1 gram (This volume does not allow for repeat testing)
Collection Processing
Do not contaminate outside of container. Do not overfill container. Do not submit watery or unformed (loose) stool. Do not use a preservative.  Specimens should be transported refrigerated (ice packs) or frozen if transport temperature is expected to exceed 40°C (104°F).
Specimen Stability Information
Specimen Type Temperature Time
​Stool ​ ​ ​Ambient ​14 days
​Refrigerate ​14 days
​Frozen 14 days
​Freeze/thaw cycles​Stable x 3
Rejection Criteria
​Serum or plasma received
​Stool contaminated with urine
​Watery or unformed (loose) stool
​Preserved stool
Useful For
Diagnosis or the exclusion of exocrine pancreatic insufficiency, which may be associated with chronic pancreatitis, cystic fibrosis, carcinoma of the pancreas, diabetes mellitus type 1 (insulin-dependent diabetes mellitus), Shwachman-Diamond syndrome, and other etiologies of pancreatic insufficiency.
Reference Range Information
• Normal: >200 μg elastase/g fecal material
• Moderate pancreatic insufficiency: 100−200 μg elastase/g fecal material
• Severe pancreatic insufficiency: <100 μg elastase/g fecal material
For more information visit:
Performing Laboratory Information
Performing Location Analytical Time​Methodology/Instrumentation
LabCorp ​4-6 days​Enzyme-linked immunosorbent assay (ELISA) based upon a monoclonal antibody-based detection system specific for pancreatic elastase-1 (PEL-1)
Reference Lab
For billing questions, see Contacts
Outreach CPTs
CPT Modifier
(if needed)
Quantity Description Comments
86253
For most current information refer to the Marshfield Laboratory online reference manual.