Skip Ribbon Commands
Skip to main content
Sign In
Navigate Up

24925 Crohn’s Prognostic, Prometheus (2001)

Crohn’s Prognostic, Prometheus (2001)
Test Code: CPROGSO
Test Components
The PROMETHEUS® Crohn's Prognostic combines proprietary serologic (anti-CBir1, anti-OMPC, DNAse sensitive pANCA) and genetic (NOD2 variants SNPs 8,12,13) markers in an innovative blood test that quantifies a patients individual probability of developing disease complications over time. The objective information from the test may allow physicians to stratify patients, assist in optimizing management strategies and may be used in risk/benefit discussions.
Useful For

Evaluate the probability of disease progression in a Crohn's disease patient by providing a personal serogenetic profile.

Specimen Requirements
Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
​Serum AND Whole Blood

​Red Top Tube (RTT) AND EDTA Lavender Top Tube (LTT)

 ​Serum Separator Tube (SST) 2 mL serum AND 2 mL EDTA whole blood ​N/A ​
Collection Processing Instructions
​Must submit both serum AND EDTA whole blood.
Specimen Stability Information
Specimen Type Temperature Time
Serum and Whole Blood​ ​ ​Ambient ​7 days
​Refrigerated ​7 days
Rejection Criteria
Not submitting both serum and whole blood.
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
​Prometheus Labs ​Monday through Friday ​4-7 days ​ELISA and PCR
Reference Lab
Prometheus Biosciences
Reference Range Information
Performing Location Reference Range
​Prometheus Labs ​Interpretive Report
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
​83520 ​ ​5 ​ASCA IgA & IgG, Anti-Ompc IgA, Anti-CBir1, Anti-12 ​
86255 ​ 2 Fluorescent antibody screen ​
​81401 ​ ​1 ​NOD2/CARD 15 PCR ​
Test Components
The PROMETHEUS® Crohn's Prognostic combines proprietary serologic (anti-CBir1, anti-OMPC, DNAse sensitive pANCA) and genetic (NOD2 variants SNPs 8,12,13) markers in an innovative blood test that quantifies a patients individual probability of developing disease complications over time. The objective information from the test may allow physicians to stratify patients, assist in optimizing management strategies and may be used in risk/benefit discussions.
Ordering Applications
Ordering Application Description
​Centricity ​Crohn's Prognostic (2001)
​Cerner ​Crohn's Prognostic (2001)
​COM ​Crohn's Prognostic (2001)
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
​Serum AND Whole Blood

​Red Top Tube (RTT) AND EDTA Lavender Top Tube (LTT)

 ​Serum Separator Tube (SST) 2 mL serum AND 2 mL EDTA whole blood ​N/A ​
Collection Processing
​Must submit both serum AND EDTA whole blood.
Specimen Stability Information
Specimen Type Temperature Time
Serum and Whole Blood​ ​ ​Ambient ​7 days
​Refrigerated ​7 days
Rejection Criteria
Not submitting both serum and whole blood.
Useful For

Evaluate the probability of disease progression in a Crohn's disease patient by providing a personal serogenetic profile.

Test Components
The PROMETHEUS® Crohn's Prognostic combines proprietary serologic (anti-CBir1, anti-OMPC, DNAse sensitive pANCA) and genetic (NOD2 variants SNPs 8,12,13) markers in an innovative blood test that quantifies a patients individual probability of developing disease complications over time. The objective information from the test may allow physicians to stratify patients, assist in optimizing management strategies and may be used in risk/benefit discussions.
Reference Range Information
Performing Location Reference Range
​Prometheus Labs ​Interpretive Report
For more information visit:
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
​Prometheus Labs ​Monday through Friday ​4-7 days ​ELISA and PCR
Reference Lab
Prometheus Biosciences
For billing questions, see Contacts
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
​83520 ​ ​5 ​ASCA IgA & IgG, Anti-Ompc IgA, Anti-CBir1, Anti-12 ​
86255 ​ 2 Fluorescent antibody screen ​
​81401 ​ ​1 ​NOD2/CARD 15 PCR ​
For most current information refer to the Marshfield Laboratory online reference manual.