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23236 Chromosome Analysis, Blood, High Resolution

Chromosome Analysis, Blood, High Resolution
Test Code: CHRC-HR
Synonyms/Keywords
Focused High Resolution Chromosome Culture, Complete High Resolution Chromosome Culture​, Karyotype
Useful For
Investigation of the chromosomal basis of many clinically recognized syndromes in the dysmorphic patient and/or patients with developmental delays. 
 
Analysis for these conditions are done at a greater band resolution.​
Specimen Requirements
Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume Pediatric Minimum Volume
​No Peripheral Blood, Whole Blood​ Sodium-heparin Green Top Tube(GTT) ​ ​ 3.0 mL​ 2.0 mL ​ 0.5 mL​
Collection Processing Instructions
Invert tube several times to assure that no clotting takes place.
 
Send pertinent clinical information and appropriate ICD-10 code(s) with the test request.  Notify Cytogenetics (800-222-5835, ext. 16388) when specimen is collected.​
 
No contingent/ hold orders will be accepted Fridays or Saturdays due to loss of specimen integrity.
Contingent/ hold orders must be resolved by the client by 1500 Friday.
If notification is not received, chromosome analysis will be performed and charged. Contact the Cytogenetics Department at 715-221-6388.
Specimen Stability Information
Specimen Type Temperature Time
Peripheral Blood​ Room Temperature​ Overnight​
Refrigerate​ If delay is longer than 24 hours​
Rejection Criteria
Frozen
Interference
If collected in tubes other than sodium heparin,(i.e. EDTA, lithium heparin)the growth and quality of the culture can be affected.
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
​Marshfield Monday - Saturday​ 2 weeks​ Manual​
Test Information
All patient specimens are prioritized by clinical indication.  Inquiries may be called to Cytogenetics (800-222-5835, ext. 16388).​
Reference Range Information
Performing Location Reference Range
Marshfield​ Interpretive Report​
See Critical Value List for list of current critical values.​ ​
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
88230​ ​ ​ Culture​ ​
88262​ ​ ​ Count 15-20 cells, 2 karyotypes​ ​
88280​ ​ ​ Additional karyotype, each ​ Charge as needed​
88283​ ​ ​ Special Banding ​ Charge as needed​
88285​ ​ ​ Additional Cell Count ​ Charge as needed​
88289​ ​ ​ Additional High Resolution Study​ ​
88291​ ​ ​ Cytogenetics Interp/report ​ Charge as needed​
Synonyms/Keywords
Focused High Resolution Chromosome Culture, Complete High Resolution Chromosome Culture​, Karyotype
Ordering Applications
Ordering Application Description
​Centricity ​Chrom Cult, Blood, High Res
​Cerner ​Chromosome Analysis, Peripheral Blood, High Resolution
​COM ​Chrom Cult, Blood, High Res
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume Pediatric Minimum Volume
​No Peripheral Blood, Whole Blood​ Sodium-heparin Green Top Tube(GTT) ​ ​ 3.0 mL​ 2.0 mL ​ 0.5 mL​
Collection Processing
Invert tube several times to assure that no clotting takes place.
 
Send pertinent clinical information and appropriate ICD-10 code(s) with the test request.  Notify Cytogenetics (800-222-5835, ext. 16388) when specimen is collected.​
 
No contingent/ hold orders will be accepted Fridays or Saturdays due to loss of specimen integrity.
Contingent/ hold orders must be resolved by the client by 1500 Friday.
If notification is not received, chromosome analysis will be performed and charged. Contact the Cytogenetics Department at 715-221-6388.
Specimen Stability Information
Specimen Type Temperature Time
Peripheral Blood​ Room Temperature​ Overnight​
Refrigerate​ If delay is longer than 24 hours​
Rejection Criteria
Frozen
Interference
If collected in tubes other than sodium heparin,(i.e. EDTA, lithium heparin)the growth and quality of the culture can be affected.
Useful For
Investigation of the chromosomal basis of many clinically recognized syndromes in the dysmorphic patient and/or patients with developmental delays. 
 
Analysis for these conditions are done at a greater band resolution.​
Reference Range Information
Performing Location Reference Range
Marshfield​ Interpretive Report​
See Critical Value List for list of current critical values.​ ​
For more information visit:
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
​Marshfield Monday - Saturday​ 2 weeks​ Manual​
For billing questions, see Contacts
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
88230​ ​ ​ Culture​ ​
88262​ ​ ​ Count 15-20 cells, 2 karyotypes​ ​
88280​ ​ ​ Additional karyotype, each ​ Charge as needed​
88283​ ​ ​ Special Banding ​ Charge as needed​
88285​ ​ ​ Additional Cell Count ​ Charge as needed​
88289​ ​ ​ Additional High Resolution Study​ ​
88291​ ​ ​ Cytogenetics Interp/report ​ Charge as needed​
For most current information refer to the Marshfield Laboratory online reference manual.