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22206 Allergen IgE Antibodies, Single Allergen, Serum

Allergen IgE Antibodies, Single Allergen, Serum
Test Code: ALLSO
Synonyms/Keywords
​ IgE Antibody, Single Allergen, Allergen-Specific Antigen
Useful For
Testing for IgE antibodies may be useful to establish the diagnosis of an allergic disease and to define the allergens responsible for eliciting signs and symptoms.
 
Testing also may be useful to identify allergens which may be responsible for allergic disease and/or anaphylactic episode, to confirm sensitization to particular allergens prior to beginning immunotherapy, and to investigate the specificity of allergic reactions to insect venom allergens, drugs, or chemical allergens.
Specimen Requirements
Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)
Pediatric Minimum Volume
(no repeat)
Serum​ Red Top Tube (RTT)​ Serum Separator Tube (SST)​ ​0.5 mL
For 1 allergen: 0.3 mL/For more than 1 allergen: (0.05 mL x number of allergens) + 0.25 mL dead space
Collection Processing Instructions
​Please indicate the allergen desired.
Specimen Stability Information
Specimen Type Temperature Time
Serum​ ​ ​Refrigerated (preferred) ​14 days
​Frozen ​90 days
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
Mayo Clinic Laboratories​​ Monday through Saturday Same day/1day​
Fluorescence Enzyme Immunoassay (FEIA)
Reference Lab
Reference Range Information
Performing Location Reference Range
​Mayo Clinic Laboratories​
ClassIgE kU/LInterpretation
0<0.35Negative
10.35-0.69Equivocal
20.70-3.49Positive
33.50-17.4Positive
417.5-49.9Strongly positive
550.0-99.9Strongly positive
6> or =100Strongly positive

Reference values apply to all ages.

Interpretation

Detection of IgE antibodies in serum (Class 1 or greater) indicates an increased likelihood of allergic disease as opposed to other etiologies and defines the allergens that may be responsible for eliciting signs and symptoms. 

The level of IgE antibodies in serum varies directly with the concentration of IgE antibodies expressed as a class score or kU/L.

Outreach CPTs
CPT Modifier
(if needed)
Quantity Description Comments
​86003
Synonyms/Keywords
​ IgE Antibody, Single Allergen, Allergen-Specific Antigen
Ordering Applications
Ordering Application Description
​COM ​Allergen, Single
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)
Pediatric Minimum Volume
(no repeat)
Serum​ Red Top Tube (RTT)​ Serum Separator Tube (SST)​ ​0.5 mL
For 1 allergen: 0.3 mL/For more than 1 allergen: (0.05 mL x number of allergens) + 0.25 mL dead space
Collection Processing
​Please indicate the allergen desired.
Specimen Stability Information
Specimen Type Temperature Time
Serum​ ​ ​Refrigerated (preferred) ​14 days
​Frozen ​90 days
Useful For
Testing for IgE antibodies may be useful to establish the diagnosis of an allergic disease and to define the allergens responsible for eliciting signs and symptoms.
 
Testing also may be useful to identify allergens which may be responsible for allergic disease and/or anaphylactic episode, to confirm sensitization to particular allergens prior to beginning immunotherapy, and to investigate the specificity of allergic reactions to insect venom allergens, drugs, or chemical allergens.
Reference Range Information
Performing Location Reference Range
​Mayo Clinic Laboratories​
ClassIgE kU/LInterpretation
0<0.35Negative
10.35-0.69Equivocal
20.70-3.49Positive
33.50-17.4Positive
417.5-49.9Strongly positive
550.0-99.9Strongly positive
6> or =100Strongly positive

Reference values apply to all ages.

Interpretation

Detection of IgE antibodies in serum (Class 1 or greater) indicates an increased likelihood of allergic disease as opposed to other etiologies and defines the allergens that may be responsible for eliciting signs and symptoms. 

The level of IgE antibodies in serum varies directly with the concentration of IgE antibodies expressed as a class score or kU/L.

For more information visit:
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
Mayo Clinic Laboratories​​ Monday through Saturday Same day/1day​
Fluorescence Enzyme Immunoassay (FEIA)
Reference Lab
For billing questions, see Contacts
Outreach CPTs
CPT Modifier
(if needed)
Quantity Description Comments
​86003
For most current information refer to the Marshfield Laboratory online reference manual.